Previously Unreported Chromosomal Aberrations of t(3;3)(q29;q23), t(4;11)(q21;q23), and t(11;18)(q10;q10) in a Patient with Accelerated Phase Ph+ CML.

Cigdem Aydin, Zafer Cetin, Ozan Salim, Orhan Kemal Yucel, Levent Undar, Sibel Berker Karauzum

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Article in Case reports in genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 48% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

Chromosomal rearrangement involving 11q23 locus in chronic myelogenous leukemia: a rare phenomenon frequently associated with disease progression and poor prognosis.Journal of hematology & oncology · 2015
Article

4 · The record

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5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Cigdem AydinDepartment of Medical Biology and Genetics, School of Medicine, Akdeniz University, 07058 Antalya, Turkey.

Zafer CetinDepartment of Medical Biology and Genetics, School of Medicine, Akdeniz University, 07058 Antalya, Turkey.

Ozan SalimDepartment of Hematology, School of Medicine, Akdeniz University, 07058 Antalya, Turkey.

Orhan Kemal YucelDepartment of Hematology, School of Medicine, Akdeniz University, 07058 Antalya, Turkey.

Levent UndarDepartment of Hematology, School of Medicine, Akdeniz University, 07058 Antalya, Turkey.

Sibel Berker KarauzumDepartment of Medical Biology and Genetics, School of Medicine, Akdeniz University, 07058 Antalya, Turkey.

Akdeniz University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic myelogenous leukemia (CML) is a clonal hematological disorder, which is characterized by the presence of the classical or variant Philadelphia translocations. During the progression to blastic phase of the disease secondary chromosomal abnormalities may emerge. Such secondary chromosomal abnormalities are nonrandom, the more frequent ones being trisomy 8 and 19, supernumerary i(17q), and extra Philadelphia chromosomes. Furthermore, a minor percentage of the patients may acquire different secondary chromosomal abnormalities including translocations between other chromosomes. We report here a patient with Ph+ CML presenting secondary chromosomal abnormalities including t(4;11)(q21;q23), t(3;3)(q29;q23) and t(11;18)(q10;q10) during the course of CML progression.

Identifiers

PMID24711936

DOI10.1155/2014/582016

PMCPMC3965933

OpenAlexW1967313148

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LicenceCC BY

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