Evidence map›Paper›PMID 24711812›Full record

ArticleDementia and geriatric cognitive disorders extra2014

Inadequate diagnostic evaluation in young patients registered with a diagnosis of dementia: a nationwide register-based study.

Lise Cronberg Salem, Birgitte Bo Andersen, T Rune Nielsen, Jette Stokholm, Martin Balslev Jørgensen, Gunhild Waldemar

Open access · goldAbstract read
In one paragraph

Article in Dementia and geriatric cognitive disorders extra, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  8. Alzheimer's disease diagnosis and management: Perspectives from around the world.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lise Cronberg SalemMemory Disorders Research Group, Danish Dementia Research Centre, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Birgitte Bo AndersenMemory Disorders Research Group, Danish Dementia Research Centre, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Denmark.
T Rune NielsenMemory Disorders Research Group, Danish Dementia Research Centre, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Jette StokholmMemory Disorders Research Group, Danish Dementia Research Centre, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Martin Balslev JørgensenPsychiatric Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark.
Gunhild WaldemarMemory Disorders Research Group, Danish Dementia Research Centre, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Denmark.
Copenhagen University Hospital · DKRigshospitalet · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEstablishing a diagnosis of dementia in young patients may be complex and have significant implications for the patient. The aim of this study was to evaluate the quality of the diagnostic work-up in young patients diagnosed with dementia in the clinical routine.

methodsTwo hundred patients were randomly selected from 891 patients aged ≤65 years registered with a diagnosis of dementia for the first time in 2008 in Danish hospitals, and 159 medical records were available for review. Three raters evaluated their medical records for the completeness of the diagnostic work-up on which the diagnosis of dementia had been based, using evidence-based guidelines for the diagnostic evaluation of dementia as reference standards.

resultsAccording to the rater review, only 111 (70%) patients met the clinical criteria for dementia. An acceptable diagnostic work-up including all items of recommended basic diagnostic evaluation was performed in only 24%, although more often (28%) in the subgroup of patients where dementia was confirmed by raters.

conclusionThis first nationwide study of unselected young patients registered with a diagnosis of dementia indicated that the concept of dementia may be misinterpreted by clinicians and that a diagnosis of dementia in the young is only rarely based on a complete basic diagnostic work-up, calling for increased competency.

Indexed as

Diagnosis of dementiaQuality of diagnostic work-upYoung patients

Identifiers

PMID24711812
PMCPMC3977222
OpenAlexW1995678357

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.