ArticleEnvironmental science and pollution research international2014
Assessment of exposure to trace metals in a cohort of pregnant women from an urban center by urine analysis in the first and third trimesters of pregnancy.
Article in Environmental science and pollution research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 80 citations in OpenAlex.
- Association between urinary heavy metal concentrations, thyroid hormones, and birth outcomes among pregnant women in Isfahan City.Scientific reports · 2025Article
- Trace Element Exposure during Pregnancy Has a Persistent Influence on Perinatal Gut Microbiota in Mother-Infant Dyads.Environmental science & technology · 2025Article
- Association between Mediterranean diet and metal mixtures concentrations in pregnant people from the New Hampshire Birth Cohort Study.The Science of the total environment · 2024Article
- Prenatal exposure to metal mixtures and lung function in children from the New Hampshire birth cohort study.Environmental research · 2023Article
- Dietary Exposure to Essential and Non-essential Elements During Infants' First Year of Life in the New Hampshire Birth Cohort Study.Exposure and health · 2023Article
- Prenatal exposure to heavy metal mixtures and anthropometric birth outcomes: a cross-sectional study.Environmental health : a global access science source · 2022Article
- Association between maternal urinary selenium during pregnancy and newborn telomere length: results from a birth cohort study.European journal of clinical nutrition · 2022Article
- Article
- Health Risk Assessment of Exposure to 15 Essential and Toxic Elements in Spanish Women of Reproductive Age: A Case Study.International journal of environmental research and public health · 2021Article
- Monitoring of urinary arsenic (As) and lead (Pb) among a sample of pregnant Iranian women.Journal of environmental health science & engineering · 2021Article
- Associations of exposure to cadmium, antimony, lead and their mixture with gestational thyroid homeostasis.Environmental pollution (Barking, Essex : 1987) · 2021Article
- Prenatal exposure to chromium (Cr) and nickel (Ni) in a sample of Iranian pregnant women: urinary levels and associated socio-demographic and lifestyle factors.Environmental science and pollution research international · 2021Article
- Demographic predictors of urinary arsenic in a low-income predominantly Hispanic pregnancy cohort in Los Angeles.Journal of exposure science & environmental epidemiology · 2021Article
- Maternal Urinary Metal and Metalloid Concentrations in Association with Oxidative Stress Biomarkers.Antioxidants (Basel, Switzerland) · 2021Article
- The Mediating Role of Placental Weight Change in the Association Between Prenatal Exposure to Thallium and Birth Weight: A Prospective Birth Cohort Study.Frontiers in public health · 2021Article
- Exposure to uranium and co-occurring metals among pregnant Navajo women.Environmental research · 2020Article
- Predictors of urinary and blood Metal(loid) concentrations among pregnant women in Northern Puerto Rico.Environmental research · 2020Article
- Urinary trace metals in association with fetal ultrasound measures during pregnancy.Environmental epidemiology (Philadelphia, Pa.) · 2020Article
- Exposure to 17 trace metals in pregnancy and associations with urinary oxidative stress biomarkers.Environmental research · 2019Article
- Urinary concentrations of environmental metals and associating factors in pregnant women.Environmental science and pollution research international · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prenatal exposure to trace metals, whether they are essential, non-essential, or toxic, must be assessed for their potential health effects in the offspring. Herein is reported an approach to this end which involved collection of urine samples during the first and third trimesters of pregnancy from 489 mothers from Sabadell (Catalonia, Spain), a highly industrialized town. These samples were analyzed for cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), selenium (Se), arsenic (As), molybdenum (Mo), cadmium (Cd), antimonium (Sb), cesium (Cs), thallium (Tl), and lead (Pb). An acid digestion method was developed and validated for inductively coupled plasma quadruple mass spectrometry (Q-ICP-MS) analysis of these 12 metals. The median concentrations of metals ranged from 0.13 to 290 μg/g creatinine, the highest levels were found for Zn and the lowest for Th. The mean concentrations of most metals except As, Ni, Th, and Pb showed statistically significant differences between both trimesters. The concentrations of Mo, Se, Cd, Cs, and Sb were higher in the first than in the third trimester, whereas the opposite was found for Co, Cu, and Zn. The concentrations of all metals in both sampling periods showed statistically significant correlations (p<0.01 for Mo and Cu, p<0.001 for the others). The significant correlations of metal urine concentrations in the first and third trimesters of pregnancy suggest that the observed differences between both periods are related to physiological changes. Accordingly, the measured urine concentrations during either the first or third trimesters can be used as estimates of exposure during pregnancy and can serve as markers for prenatal intake of these metals in the studied cohort.
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