Evidence map›Paper›PMID 24710522›Full record

ArticleJAMA pediatrics2014

Higher crash and near-crash rates in teenaged drivers with lower cortisol response: an 18-month longitudinal, naturalistic study.

Marie Claude Ouimet, Thomas G Brown, Feng Guo, Sheila G Klauer, Bruce G Simons-Morton, Youjia Fang, Suzanne E Lee, Christina Gianoulakis, Thomas A Dingus

Abstract read
In one paragraph

Article in JAMA pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
31.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  4. Observational
  5. Evaluation of risk change-point for novice teenage drivers.Accident; analysis and prevention · 2017
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Marie Claude OuimetFaculty of Medicine and Health Sciences, University of Sherbrooke, Longueuil, Quebec, Canada2Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Thomas G BrownDouglas Hospital Research Centre, McGill University, Montreal, Quebec, Canada.
Feng GuoVirginia Tech Transportation Institute, Blacksburg, Virginia5Department of Statistics, Virginia Tech, Blacksburg, Virginia.
Sheila G KlauerVirginia Tech Transportation Institute, Blacksburg, Virginia.
Bruce G Simons-MortonEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Youjia FangDepartment of Statistics, Virginia Tech, Blacksburg, Virginia.
Suzanne E LeeVirginia Tech Transportation Institute, Blacksburg, Virginia.
Christina GianoulakisDouglas Hospital Research Centre, McGill University, Montreal, Quebec, Canada.
Thomas A DingusVirginia Tech Transportation Institute, Blacksburg, Virginia.
Virginia Tech · USNational Institutes of Health · USVirginia Tech Transportation InstituteDouglas Mental Health University Institute · CAMcGill University · CA

Funding

Preventing Motor Vehicle Crashes Among Young DriversZIAHD001707 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SIMONS-MORTON, BRUCE G · 2009 to 2019
$4.0M
Intramural NIH HHS ZIA HD001707NICHD NIH HHS N01-HD-5-3405
6 · The paper itself

Abstract

importanceRoad traffic crashes are one of the leading causes of injury and death among teenagers worldwide. Better understanding of the individual pathways to driving risk may lead to better-targeted intervention in this vulnerable group.

objectiveTo examine the relationship between cortisol, a neurobiological marker of stress regulation linked to risky behavior, and driving risk. DESIGN, SETTING, AND

participantsThe Naturalistic Teenage Driving Study was designed to continuously monitor the driving behavior of teenagers by instrumenting vehicles with kinematic sensors, cameras, and a global positioning system. During 2006-2008, a community sample of 42 newly licensed 16-year-old volunteer participants in the United States was recruited and driving behavior monitored. It was hypothesized in teenagers that higher cortisol response to stress is associated with (1) lower crash and near-crash (CNC) rates during their first 18 months of licensure and (2) faster reduction in CNC rates over time. MAIN OUTCOMES AND MEASURES: Participants' cortisol response during a stress-inducing task was assessed at baseline, followed by measurement of their involvement in CNCs and driving exposure during their first 18 months of licensure. Mixed-effect Poisson longitudinal regression models were used to examine the association between baseline cortisol response and CNC rates during the follow-up period.

resultsParticipants with a higher baseline cortisol response had lower CNC rates during the follow-up period (exponential of the regression coefficient, 0.93; 95% CI, 0.88-0.98) and faster decrease in CNC rates over time (exponential of the regression coefficient, 0.98; 95%, CI, 0.96-0.99). CONCLUSIONS AND RELEVANCE: Cortisol is a neurobiological marker associated with teenaged-driving risk. As in other problem-behavior fields, identification of an objective marker of teenaged-driving risk promises the development of more personalized intervention approaches.

Indexed as

Automobile DrivingAccidents, TrafficAdolescentAdolescent BehaviorBiomarkersFemaleHumansHydrocortisoneLongitudinal StudiesMaleRegression AnalysisRisk-TakingStress, PsychologicalUnited StatesBiomarkersHydrocortisone

Identifiers

PMID24710522
PMCPMC4139916
OpenAlexW2138892065

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.