ArticleThe American journal of gastroenterology2014
Assessing bolus retention in achalasia using high-resolution manometry with impedance: a comparator study with timed barium esophagram.
Article in The American journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06883175 (Evolution of the Chicago Classification), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evolution of the Chicago Classification: Bridging Physiology and Mechanics
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- ACG Clinical Guidelines: Clinical Use of Esophageal Physiologic Testing.The American journal of gastroenterology · 2020Guideline
- High-Resolution Impedance Manometry (HRIM) Using Yogurt (Viscosity Matched to Barium) for Bolus Clearance After Therapy in Achalasia.Digestive diseases and sciences · 2026Article
- PPI-Refractory GERD in Systemic Sclerosis Is Driven by Distinct Esophageal and Gastric Motility Abnormalities.medRxiv : the preprint server for health sciences · 2026Article
- Validating Impedance/pH Sensors for Measuring Oesophageal Transit:Sensors (Basel, Switzerland) · 2025Article
- Article
- Advances in the Diagnosis and Management of Achalasia and Achalasia-Like Syndromes: Insights From HRM and FLIP.Gastro hep advances · 2023Article
- Normative values of intra-bolus pressure and esophageal compliance based on 4D high-resolution impedance manometry.Neurogastroenterology and motility · 2022Article
- Heterogeneity of primary and secondary peristalsis in systemic sclerosis: A new model of "scleroderma esophagus".Neurogastroenterology and motility · 2022Article
- Elevated average maximum intrabolus pressure on high-resolution manometry is associated with esophageal dysmotility and delayed esophageal emptying on timed barium esophagram.BMC gastroenterology · 2022Article
- Dysphagia: Novel and Emerging Diagnostic Modalities.Gastroenterology clinics of North America · 2021Review
- Detecting Oropharyngeal and Esophageal Emptying by Submental Ultrasonography and High-Resolution Impedance Manometry: Intubated vs. Non-Intubated Video-Assisted Thoracoscopic Surgery.Diagnostics (Basel, Switzerland) · 2020Article
- The Role of Automatically Generated Chicago Classification in Delayed Achalasia Diagnosis.ACG case reports journal · 2020Article
- New Developments in Esophageal Motility Testing.Current treatment options in gastroenterology · 2019Review
- Utility of Esophageal High-Resolution Manometry in Clinical Practice: First, Do HRM.Digestive diseases and sciences · 2018Review
- Advances in Management of Esophageal Motility Disorders.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2018Review
- Roles of High-resolution Manometry in Predicting Incomplete Bolus Transit in Patients With Dysphagia.Journal of clinical gastroenterology · 2018Article
- Assessment of Esophageal High-Resolution Impedance Manometry in Patients with Nonobstructive Dysphagia.Gastroenterology research and practice · 2018Article
- Achalasia: It Is Not All Black and White.Current gastroenterology reports · 2017Review
- How to Optimally Apply Impedance in the Evaluation of Esophageal Dysmotility.Current gastroenterology reports · 2016Review
- Correlation Between Timed Barium Esophagogram and Esophageal Transit Scintigraphy Results in Achalasia.Digestive diseases and sciences · 2015Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectivesThe aim of this study was to assess whether high-resolution impedance manometry (HRIM) could be used to assess bolus retention similar to the timed barium esophagram (TBE).
methodsTwenty achalasia patients (10 males, aged 21-79 years) were prospectively evaluated with HRIM and TBE to determine the correlation between barium column height and the impedance bolus height (IBH). The TBE protocol used a 200-ml barium challenge and the HRIM protocol used a 200-ml saline challenge protocol. Both protocols were performed in an upright position and the heights of the barium and impedance columns were measured at 1 and 5 min. Analysis of IBH was performed with a topographic technique and a spatial impedance variation plot.
resultsThere was no significant difference between the median IBH and barium column at 1 min (IBH: 12.0 cm (interquartile range (IQR), 8.0-18.0); TBE: 12.0 cm (IQR, 7.0-19.0); P=0.90) or at 5 min (IBH: 11.0 cm (IQR, 1.0-17.0); TBE: 9.0 cm (IQR, 4.0-12.0); P=0.47). In addition, the correlation between the two measurements at 1 and 5 min was 0.60 and 0.86, respectively. Using a barium column or impedance height of >5.0 as a definition of bolus retention was associated with 75% concordance at 1 min and 95% concordance at 5 min.
conclusionsThere was excellent agreement between TBE and high-resolution impedance manometry (HRIM) for assessing bolus retention at 5 min. Thus, HRM with impedance may be used as a single test to assess bolus retention and motor function in the management of achalasia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.