Evidence map›Paper›PMID 24709799›Full record

ArticleCells2013

Fluorescein derivatives in intravital fluorescence imaging.

Thomas A Robertson, Florestan Bunel, Michael S Roberts

Open access · goldAbstract read
In one paragraph

Article in Cells, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Fluorescence quenching by metal centered porphyrins and poryphyrin enzymes.American journal of physiology. Regulatory, integrative and comparative physiology · 2017
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Thomas A RobertsonTherapeutics Research Centre, School of Pharmacy and Medical Sciences, Division of Health Sciences, University of South Australia and Basil Hetzel Institute for Medical Research, GPO Box 2471, Adelaide, SA, 5001, Australia. tom.robertson@unisa.edu.au.
Florestan BunelUniversité Libre de Bruxelles, Campus Plaine CP205, Boulevard du Triomphe, 1050 Bruxelles, Belgium.
Michael S RobertsTherapeutics Research Centre, School of Pharmacy and Medical Sciences, Division of Health Sciences, University of South Australia and Basil Hetzel Institute for Medical Research, GPO Box 2471, Adelaide, SA, 5001, Australia.
University of South Australia · AUUniversité Libre de Bruxelles · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravital fluorescence microscopy enables the direct imaging of fluorophores in vivo and advanced techniques such as fluorescence lifetime imaging (FLIM) enable the simultaneous detection of multiple fluorophores. Consequently, it is now possible to record distribution and metabolism of a chemical in vivo and to optimise the delivery of fluorophores in vivo. Recent clinical applications with fluorescein and other intravital fluorescent stains have occurred in neurosurgery, dermatology [including photodynamic therapy (PDT)] and endomicroscopy. Potential uses have been identified in periodontal disease, skin graft and cancer surgery. Animal studies have demonstrated that diseased tissue can be specifically stained with fluorophore conjugates. This review focuses on the fluorescein derived fluorophores in common clinical use and provides examples of novel applications from studies in tissue samples.

Identifiers

PMID24709799
PMCPMC3972669
OpenAlexW2002799584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.