Evidence map›Paper›PMID 24709663›Full record

ArticleJournal of cardiac failure2014

Prevalence of heart failure signs and symptoms in a large primary care population identified through the use of text and data mining of the electronic health record.

Rajakrishnan Vijayakrishnan, Steven R Steinhubl, Kenney Ng, Jimeng Sun, Roy J Byrd, Zahra Daar, Brent A Williams, Christopher deFilippi, Shahram Ebadollahi, Walter F Stewart

Abstract read
In one paragraph

Article in Journal of cardiac failure, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. A Holistic View of Advanced Heart Failure.Life (Basel, Switzerland) · 2022
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Rajakrishnan VijayakrishnanDepartment of Cardiology, Geisinger Medical Center, Danville, Pennsylvania; Center for Health Research, Geisinger Medical Center, Danville, Pennsylvania.
Steven R SteinhublDepartment of Cardiology, Geisinger Medical Center, Danville, Pennsylvania; Center for Health Research, Geisinger Medical Center, Danville, Pennsylvania; Scripps Translational Science Institute, La Jolla, California. Electronic address: steinhub@scripps.edu.
Kenney NgT. J. Watson Research Center, IBM, Hawthorne, New York.
Jimeng SunT. J. Watson Research Center, IBM, Hawthorne, New York; Georgia Institute of Technology, Atlanta, Georgia.
Roy J ByrdT. J. Watson Research Center, IBM, Hawthorne, New York.
Zahra DaarDepartment of Cardiology, Geisinger Medical Center, Danville, Pennsylvania; Center for Health Research, Geisinger Medical Center, Danville, Pennsylvania.
Brent A WilliamsDepartment of Cardiology, Geisinger Medical Center, Danville, Pennsylvania; Center for Health Research, Geisinger Medical Center, Danville, Pennsylvania.
Christopher deFilippiUniversity of Maryland, Baltimore, Maryland.
Shahram EbadollahiT. J. Watson Research Center, IBM, Hawthorne, New York.
Walter F StewartSutter Health, Concord, California.

Funding

Early Detection of Heart Failure via the Electronic Health Record in Primary CareR01HL116832 · NHLBI · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI STEWART, WALTER F · 2013 to 2015
$1.5M
NHLBI NIH HHS R01 HL116832
6 · The paper itself

Abstract

backgroundThe electronic health record (EHR) contains a tremendous amount of data that if appropriately detected can lead to earlier identification of disease states such as heart failure (HF). Using a novel text and data analytic tool we explored the longitudinal EHR of over 50,000 primary care patients to identify the documentation of the signs and symptoms of HF in the years preceding its diagnosis. METHODS AND

resultsRetrospective analysis consisted of 4,644 incident HF cases and 45,981 group-matched control subjects. Documentation of Framingham HF signs and symptoms within encounter notes were carried out with the use of a previously validated natural language processing procedure. A total of 892,805 affirmed criteria were documented over an average observation period of 3.4 years. Among eventual HF cases, 85% had ≥1 criterion within 1 year before their HF diagnosis, as did 55% of control subjects. Substantial variability in the prevalence of individual signs and symptoms were found in both case and control subjects.

conclusionsHF signs and symptoms are frequently documented in a primary care population as identified through automated text and data mining of EHRs. Their frequent identification demonstrates the rich data available within EHRs that will allow for future work on automated criterion identification to help develop predictive models for HF.

Indexed as

Population SurveillancePrimary Health CareAgedAged, 80 and overCase-Control StudiesCohort StudiesData MiningElectronic Health RecordsFemaleHeart FailureHumansMaleMiddle AgedPrevalenceRetrospective Studieselectronic health recordsHeart failurenatural language processing

Identifiers

PMID24709663
PMCPMC4083004

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.