Evidence map›Paper›PMID 24709586›Full record

ReviewVaccine2014

Optimizing benefits of influenza virus vaccination during pregnancy: potential behavioral risk factors and interventions.

Lisa M Christian

Open access · greenAbstract readReview
In one paragraph

Review in Vaccine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Influenza in High-Risk Hosts-Lessons Learned from Animal Models.Cold Spring Harbor perspectives in medicine · 2020
    Review
  4. Article
  5. Article
  6. Observational
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Lisa M ChristianDepartment of Psychiatry, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States; The Institute for Behavioral Medicine Research, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States; Department of Psychology, The Ohio State University, Columbus, OH 43210, United States; Department of Obstetrics and Gynecology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, United States. Electronic address: lisa.christian@osumc.edu.
The Ohio State University Wexner Medical Center · US

Funding

Maternal Stress, Obesity, and Influenza Virus Vaccine Immunogenicity in PregnancyR01NR013661 · NINR · OHIO STATE UNIVERSITY · PI CHRISTIAN, LISA MICHELLE · 2013 to 2017
$1.9M
Stress, Race, and Immune Adaptation Across Pregnancy: Predictors of Preterm BirthR21HD067670 · NICHD · OHIO STATE UNIVERSITY · PI CHRISTIAN, LISA MICHELLE · 2011 to 2012
$419k
Physiological reactivity to acute stress during pregnancyR21HD061644 · NICHD · OHIO STATE UNIVERSITY · PI CHRISTIAN, LISA MICHELLE · 2009 to 2010
$402k
NICHD NIH HHS R21 HD061644NICHD NIH HHS R21 HD067670NINR NIH HHS R01 NR01366NINR NIH HHS R01 NR013661
6 · The paper itself

Abstract

Pregnant women and infants are at high risk for complications, hospitalization, and death due to influenza. It is well-established that influenza vaccination during pregnancy reduces rates and severity of illness in women overall. Maternal vaccination also confers antibody protection to infants via both transplacental transfer and breast milk. However, as in the general population, a relatively high proportion of pregnant women and their infants do not achieve protective antibody levels against influenza virus following maternal vaccination. Behavioral factors, particularly maternal weight and stress exposure, may affect initial maternal antibody responses, maintenance of antibody levels over time (i.e., across pregnancy), as well as the efficiency of transplacental antibody transfer to the fetus. Conversely, behavioral interventions including acute exercise and stress reduction can enhance immune protection following vaccination. Such behavioral interventions are particularly appealing in pregnancy because they are safe and non-invasive. The identification of individual risk factors for poor responses to vaccines and the application of appropriate interventions represent important steps towards personalized health care.

Indexed as

PregnancyAntibodies, ViralAntibody FormationExerciseFemaleHealth BehaviorHealth PromotionHumansInfant, NewbornInfluenza VaccinesPregnancy Complications, InfectiousRisk FactorsStress, PsychologicalVaccinationAntibodies, ViralInfluenza VaccinesAntibody responseBehavioralexerciseFlu shotInfluenza virus vaccineInterventionObesityPregnancyPregnantPsychological stress

Identifiers

PMID24709586
PMCPMC4043397
OpenAlexW2018025001

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.