ReviewCurrent opinion in structural biology2014
Protein structure determination by MicroED.
Review in Current opinion in structural biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed.
- Multimodal Nanoscale Mapping of Local Structure and COJournal of the American Chemical Society · 2026Article
- Strategies for mitigating radiation damage and improving data completeness in 3D electron diffraction of protein crystals.Acta crystallographica. Section D, Structural biology · 2026Article
- Review
- Unraveling atomic complexity from frozen samples.Structural dynamics (Melville, N.Y.) · 2025Article
- MicroED structure of the C11 cysteine protease clostripain.Journal of structural biology: X · 2024Article
- AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography.Acta crystallographica. Section D, Structural biology · 2024Article
- Unraveling the Structure of Meclizine Dihydrochloride with MicroED.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- 3D electron diffraction analysis of a novel, mechanochemically synthesized supramolecular organic framework based on tetrakis-4-(4-pyridyl)phenylmethane.Acta crystallographica Section B, Structural science, crystal engineering and materials · 2023Article
- Unraveling the Structure of Meclizine Dihydrochloride with MicroED.bioRxiv : the preprint server for biology · 2023Article
- From Powders to Single Crystals: A Crystallographer's Toolbox for Small-Molecule Structure Determination.Molecular pharmaceutics · 2022Article
- Metalloprotein catalysis: structural and mechanistic insights into oxidoreductases from neutron protein crystallography.Acta crystallographica. Section D, Structural biology · 2021Review
- Protein and Small Molecule Structure Determination by the Cryo-EM Method MicroED.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Studying Membrane Protein Structures by MicroED.Methods in molecular biology (Clifton, N.J.) · 2021Article
- The complementarity of serial femtosecond crystallography and MicroED for structure determination from microcrystals.Current opinion in structural biology · 2019Review
- Automated electron diffraction tomography - development and applications.Acta crystallographica Section B, Structural science, crystal engineering and materials · 2019Article
- Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface.Nature communications · 2019Article
- Transcription with a laser: Radiation-damage-free diffraction of RNA Polymerase II crystals.Methods (San Diego, Calif.) · 2019Article
- The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination.ACS central science · 2018Article
- MicroED: a versatile cryoEM method for structure determination.Emerging topics in life sciences · 2018Article
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
In this review we discuss the current advances relating to structure determination from protein microcrystals with special emphasis on the newly developed method called MicroED. This method uses a transmission electron cryo-microscope to collect electron diffraction data from extremely small 3-dimensional (3D) crystals. MicroED has been used to solve the 3D structure of the model protein lysozyme to 2.9Å resolution. As the method further matures, MicroED promises to offer a unique and widely applicable approach to protein crystallography using nanocrystals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.