ArticleParasites & vectors2014
Temporal and spatial dynamics of trypanosomes infecting the brush-tailed bettong (Bettongia penicillata): a cautionary note of disease-induced population decline.
Article in Parasites & vectors, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 37 citations in OpenAlex.
- A reference genome for the critically endangered woylie,GigaByte (Hong Kong, China) · 2021Article
- Epidemiology of Trypanosomiasis in Wildlife-Implications for Humans at the Wildlife Interface in Africa.Frontiers in veterinary science · 2021Review
- Species-level identification of trypanosomes infecting Australian wildlife by High-Resolution Melting - Real Time Quantitative Polymerase Chain Reaction (HRM-qPCR).International journal for parasitology. Parasites and wildlife · 2020Article
- Blood Parasites in Endangered Wildlife-Trypanosomes Discovered During a Survey of Haemoprotozoa from the Tasmanian Devil.Pathogens (Basel, Switzerland) · 2020Article
- Meta-transcriptomic identification of Trypanosoma spp. in native wildlife species from Australia.Parasites & vectors · 2020Article
- Altered parasite community structure in an endangered marsupial following translocation.International journal for parasitology. Parasites and wildlife · 2019Article
- Increased Trypanosoma spp. richness and prevalence of haemoparasite co-infection following translocation.Parasites & vectors · 2019Article
- Debilitating disease in a polyparasitised woylie (International journal for parasitology. Parasites and wildlife · 2018Article
- The marsupial trypanosome Trypanosoma copemani is not an obligate intracellular parasite, although it adversely affects cell health.Parasites & vectors · 2018Article
- Trypanosome co-infections increase in a declining marsupial population.International journal for parasitology. Parasites and wildlife · 2018Article
- Next generation sequencing reveals widespread trypanosome diversity and polyparasitism in marsupials from Western Australia.International journal for parasitology. Parasites and wildlife · 2018Article
- Haematozoa of wild catfishes in northern Australia.International journal for parasitology. Parasites and wildlife · 2018Article
- Article
- Morphological and molecular description of Ixodes woyliei n. sp. (Ixodidae) with consideration for co-extinction with its critically endangered marsupial host.Parasites & vectors · 2017Article
- Article
- Temporal Patterns in the Abundance of a Critically Endangered Marsupial Relates to Disturbance by Roads and Agriculture.PloS one · 2016Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe brush-tailed bettong or woylie (Bettongia penicillata) is on the brink of extinction. Its numbers have declined by 90% since 1999, with their current distribution occupying less than 1% of their former Australian range. Woylies are known to be infected with three different trypanosomes (Trypanosoma vegrandis, Trypanosoma copemani and Trypanosoma sp. H25) and two different strains of T. copemani that vary in virulence. However, the role that these haemoparasites have played during the recent decline of their host is unclear and is part of ongoing investigation.
methodsWoylies were sampled from five locations in southern Western Australia, including two neighbouring indigenous populations, two enclosed (fenced) populations and a captive colony. PCR was used to individually identify the three different trypanosomes from blood and tissues of the host, and to investigate the temporal and spatial dynamics of trypanosome infections.
resultsThe spatial pattern of trypanosome infection varied among the five study sites, with a greater proportion of woylies from the Perup indigenous population being infected with T. copemani than from the neighbouring Kingston indigenous population. For an established infection, T. copemani detection was temporally inconsistent. The more virulent strain of T. copemani appeared to regress at a faster rate than the less virulent strain, with the infection possibly transitioning from the acute to chronic phase. Interspecific competition may also exist between T. copemani and T. vegrandis, where an existing T. vegrandis infection may moderate the sequential establishment of the more virulent T. copemani.
conclusionIn this study, we provide a possible temporal connection implicating T. copemani as the disease agent linked with the recent decline of the Kingston indigenous woylie population within the Upper Warren region of Western Australia. The chronic association of trypanosomes with the internal organs of its host may be potentially pathogenic and adversely affect their long term fitness and coordination, making the woylie more susceptible to predation.
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