ArticleJournal of clinical periodontology2014
Periodontal infection, impaired fasting glucose and impaired glucose tolerance: results from the Continuous National Health and Nutrition Examination Survey 2009-2010.
Article in Journal of clinical periodontology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04830969 (Impact of Periodontal Therapy on Patients With Diabetes), which is not on this map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Periodontal Therapy on Patients With Diabetes: A Pilot Study
Who cites it
35 citing papers in PubMed, 65 citations in OpenAlex.
- Community interventions improve diabetes management and oral health in type 2 diabetes patients with chronic periodontitis.Scientific reports · 2025Trial
- Associations Between Socioeconomic, Spatial and Educational Factors and Midlife Periodontal Disease Risk: Evidence From 'High School and Beyond'.Journal of clinical periodontology · 2025Article
- Association of Periodontal Condition With Impaired Glucose Tolerance: Results of a 15-Year Follow-Up Study.Clinical and experimental dental research · 2024Article
- Association Between `Life's Essential 8' and Periodontitis: A Cross-Sectional Study From the NHANES Database.International dental journal · 2024Article
- Gingipain from Porphyromonas gingivalis causes insulin resistance by degrading insulin receptors through direct proteolytic effects.International journal of oral science · 2024Article
- Clinical attachment loss is cross-sectionally associated with elevated glucose among adults without diabetes.Journal of clinical periodontology · 2024Article
- The association between cystic fibrosis-related diabetes and periodontitis in adults: A pilot cross-sectional study.PloS one · 2024Article
- Periodontitis as a promoting factor of T2D: current evidence and mechanisms.International journal of oral science · 2023Review
- Review
- Glycemic and Insulin Status in Periodontitis Patients using the Homeostasis Model Assessment (HOMA): A Pilot Study.Oral health & preventive dentistry · 2023Article
- Impact of Impaired Glucose Metabolism on Periodontitis Progression over Three Years.Dentistry journal · 2022Article
- Article
- Periodontal Disease as a Predictor of Undiagnosed Diabetes or Prediabetes in Dental Patients.European journal of dentistry · 2021Article
- Nutrition as a Key Modifiable Factor for Periodontitis and Main Chronic Diseases.Journal of clinical medicine · 2021Article
- Can gingival crevicular blood effectively screen for diabetes in Chinese patients with moderate to severe periodontitis? A pilot study.Journal of dental sciences · 2021Article
- Periodontal disease and incident dementia: The Atherosclerosis Risk in Communities Study (ARIC).Neurology · 2020Article
- [Associations of impaired glucose metabolism with chronic peridontitis in pre-diabetes patients].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020Article
- Prediabetes and diabetes prevalence in the Workers' Oral Health Study.Clinical oral investigations · 2019Article
- Subgingival Microbiota and Longitudinal Glucose Change: The Oral Infections, Glucose Intolerance and Insulin Resistance Study (ORIGINS).Journal of dental research · 2019Article
- Association between Diabetes Mellitus and Periodontal Diseases: A Survey of the Opinions of Dental Professionals.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2019Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
aimWe investigated the relationship between periodontal disease, a clinical manifestation of periodontal infection, and pre-diabetes.
methodsThe National Health and Nutrition Examination Survey, 2009-2010 enrolled 1165 diabetes-free adults (51% female) aged 30-80 years (mean ± SD=50 ± 14) who received a full-mouth periodontal examination and an oral glucose tolerance test. Participants were classified as having none/mild, moderate or severe periodontitis and also according to mean probing depth ≥ 2.19 mm or attachment loss ≥ 1.78 mm, (respective 75th percentiles). Pre-diabetes was defined according to ADA criteria as either: (i) impaired fasting glucose (IFG) or impaired glucose tolerance (IGT). In multivariable logistic regression models, the odds of IFG and IGT were regressed on levels of periodontitis category.
resultsThe odds ratios and 95% confidence intervals for having IGT among participants with moderate or severe periodontitis, relative to participants with none/mild periodontitis were 1.07 [0.50, 2.25] and 1.93 [1.18, 3.17], p = 0.02. The ORs for having IFG were 1.14 [0.74, 1.77] and 1.12 [0.58, 2.18], p = 0.84. PD ≥ 75 th percentile was related to a 105% increase in the odds of IGT: OR [95% CI] = 2.05 [1.24, 3.39], p = 0.005.
conclusionsPeriodontal infection was positively associated with prevalent impaired glucose tolerance in a cross-sectional study among a nationally representative sample.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.