ArticleJournal of clinical hypertension (Greenwich, Conn.)2014
Left atrial enlargement in the early stage of hypertensive heart disease: a common but ignored condition.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Assessing the causal role of hypertension on left atrial and left ventricular structure and function: A two-sample Mendelian randomization study.Frontiers in cardiovascular medicine · 2022Pooled it
- Maximum home blood pressure readings are associated with left atrial diameter in essential hypertensives.Journal of human hypertension · 2018Trial
- Dapagliflozin is associated with a reduction in left atrial volume index in type 2 diabetes mellitus without established cardiovascular disease.Acta diabetologica · 2026Observational
- The impact of body mass index and epicardial adipose tissue on left atrial function in hypertensive patients: a cardiac magnetic resonance feature tracking study.Quantitative imaging in medicine and surgery · 2026Article
- Echocardiographic Alterations in Patients With Hypertension Treated With the "Quadpill".Journal of the American Heart Association · 2026Article
- Development and validation of a logistic regression-based nomogram for predicting 1-year all-cause death and heart failure rehospitalization in hypertensive patients with chronic heart failure.Frontiers in cardiovascular medicine · 2026Article
- Genetic determinants of the phenotype in a Swedish cohort of patients with hypertrophic cardiomyopathy.Scientific reports · 2025Article
- Article
- Predictive value of remnant cholesterol for left ventricular hypertrophy and prognosis in hypertensive patients with heart failure: a prospective study.Lipids in health and disease · 2024Article
- Interaction effect of hypertension and obesity on left atrial phasic function: a three-dimensional echocardiography study.Quantitative imaging in medicine and surgery · 2023Article
- Serum Vitamin D Levels, Disease Activity Score-28 for Rheumatoid Arthritis with C-Reactive Protein (DAS28-CRP), and Cardiac Remodeling Determined by Ventricular Dimensions and Left Atrium Diameter in Patients with Rheumatoid Arthritis: A Prospective Observational Study.Medical science monitor : international medical journal of experimental and clinical research · 2023Observational
- Specific inflammatory profile of acute ischemic stroke patients with left atrial enlargement.Frontiers in cardiovascular medicine · 2023Article
- Artificial Intelligence-Enabled Electrocardiogram Estimates Left Atrium Enlargement as a Predictor of Future Cardiovascular Disease.Journal of personalized medicine · 2022Article
- Effect of different alcohol consumption levels on the left atrial size: A cross-sectional study in rural China.Anatolian journal of cardiology · 2022Article
- Article
- Association between Light-Induced Dynamic Dilation of Retinal Vessels and Echocardiographic Parameters of the Left Ventricular Function in Hypertensive Patients.Medicina (Kaunas, Lithuania) · 2020Article
- Different associations between left atrial size and 2.5-year clinical outcomes in patients with anterior versus non-anterior wall ST-elevation myocardial infarction.The Journal of international medical research · 2020Article
- Pathophysiology of Hypertensive Heart Disease: Beyond Left Ventricular Hypertrophy.Current hypertension reports · 2020Review
- Diagnostic accuracy of left atrial remodelling and natriuretic peptide levels for preclinical heart failure.ESC heart failure · 2019Article
- The relation between blood pressure components and left atrial volume in the context of left ventricular mass index.Medicine · 2017Observational
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
How to identify the early signs of hypertensive heart disease is the key to block or reverse the process of heart failure. The aim of this study was to evaluate the predictive value of left atrial (LA) enlargement in the early stage of hypertensive heart disease and to explore the correlations between LA enlargement and heart failure with normal ejection fraction (HFnEF), as well as the metabolic syndrome (MetS). Baseline clinical characteristics, biochemical indices, electrocardiographic and echocardiographic data were collected from 341 consecutive patients with essential hypertension. Among those patients, LA enlargement was more frequently presented than LV enlargement (57.2% vs 17.9%). Compared with patients without HFnEF, the prevalence of LA enlargement was higher in patients with HFnEF (82.9% vs 49.0%, P<.0001). From grade 2 to grade 3 hypertension, LA size was significantly larger in patients with MetS (P<.01) than those without. Multivariate linear regression analyses showed that age, body mass index, waist circumference, triglyceride level, and left ventricular diameter were independent predictors of LA enlargement. The simple measurement for identification of LA enlargement potentially allows early recognition of those patients at risk for heart failure, particularly among patients with MetS.
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