ArticleBMC developmental biology2014
Integrated proteomic and transcriptomic analysis of the Aedes aegypti eggshell.
Article in BMC developmental biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- Review
- Odorant-binding proteins and chemosensory proteins in insects: structural insights, functional plasticity, and prospects for targeted pest management.Molecular biology reports · 2026Review
- Species-specific impacts of radiofrequency exposure on the structural and morphological characteristics of Aedes aegypti and Aedes albopictus eggs.Scientific reports · 2026Article
- Chromosome-scale genome assembly and developmental transcriptome of Aedes triseriatus, vector of La Crosse virus.BMC genomics · 2026Article
- Adaptive genomic signatures of globally invasive populations of the yellow fever mosquito Aedes aegypti.Nature ecology & evolution · 2025Article
- Review
- Transcription factor E93 regulates vitellogenesis via the vitelline membrane protein 26Ab gene in Chilo Suppressalis.Molecular biology reports · 2024Article
- Article
- Activation of the G protein-coupled sulfakinin receptor inhibits blood meal intake in the mosquito Aedes aegypti.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Elucidation of ejaculatory bulb proteins in Bemisia tabaci Asia-1 and Asia II-1 and confirmation of their mating transfer via RNAi.Molecular biology reports · 2024Article
- Knockdown of Sec16 causes early lethality and defective deposition of the protein Rp30 in the eggshell of the vectorFrontiers in cell and developmental biology · 2024Article
- Protein localization and potential function of lipocalin in Reticulitermes speratus queens.PloS one · 2024Article
- Article
- Expression and purification of Drosophila OBP44a with the aids of LC-MS and NMR.Protein expression and purification · 2023Article
- Article
- Transcriptome analysis used to identify and characterize odorant binding proteins in Agasicles hygrophila (Coleoptera: Chryspmelidae).Journal of insect science (Online) · 2023Article
- Vitellogenin genes are transcribed in Culex quinquefasciatus ovary.Memorias do Instituto Oswaldo Cruz · 2023Article
- RNA Interference of Phenoloxidases of the Fall Armyworm,Insects · 2022Article
- Vitelline Membrane Protein 26 Mutagenesis, Using CRISPR/Cas9, Results in Egg Collapse inInternational journal of molecular sciences · 2022Article
- Metal ions in insect reproduction: a crosstalk between reproductive physiology and immunity.Current opinion in insect science · 2022Review
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
backgroundMosquito eggshells show remarkable diversity in physical properties and structure consistent with adaptations to the wide variety of environments exploited by these insects. We applied proteomic, transcriptomic, and hybridization in situ techniques to identify gene products and pathways that participate in the assembly of the Aedes aegypti eggshell. Aedes aegypti population density is low during cold and dry seasons and increases immediately after rainfall. The survival of embryos through unfavorable periods is a key factor in the persistence of their populations. The work described here supports integrated vector control approaches that target eggshell formation and result in Ae. aegypti drought-intolerant phenotypes for public health initiatives directed to reduce mosquito-borne diseases.
resultsA total of 130 proteins were identified from the combined mass spectrometric analyses of eggshell preparations.
conclusionsClassification of proteins according to their known and putative functions revealed the complexity of the eggshell structure. Three novel Ae. aegypti vitelline membrane proteins were discovered. Odorant-binding and cysteine-rich proteins that may be structural components of the eggshell were identified. Enzymes with peroxidase, laccase and phenoloxidase activities also were identified, and their likely involvements in cross-linking reactions that stabilize the eggshell structure are discussed.
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