Evidence map›Paper›PMID 24707485›Full record

ArticleBioMed research international2014

Approaches for recognizing disease genes based on network.

Quan Zou, Jinjin Li, Chunyu Wang, Xiangxiang Zeng

Abstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. LanDis: the disease landscape explorer.European journal of human genetics : EJHG · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Quan ZouSchool of Information Science and Technology, Xiamen University, Xiamen 361005, China.
Jinjin LiSchool of Information Science and Technology, Xiamen University, Xiamen 361005, China.
Chunyu WangSchool of Computer Science and Technology, Harbin Institute of Technology, Harbin 150001, China.
Xiangxiang ZengSchool of Information Science and Technology, Xiamen University, Xiamen 361005, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diseases are closely related to genes, thus indicating that genetic abnormalities may lead to certain diseases. The recognition of disease genes has long been a goal in biology, which may contribute to the improvement of health care and understanding gene functions, pathways, and interactions. However, few large-scale gene-gene association datasets, disease-disease association datasets, and gene-disease association datasets are available. A number of machine learning methods have been used to recognize disease genes based on networks. This paper states the relationship between disease and gene, summarizes the approaches used to recognize disease genes based on network, analyzes the core problems and challenges of the methods, and outlooks future research direction.

Indexed as

Artificial IntelligenceDatabases, GeneticDiseaseGene Expression ProfilingGene Regulatory NetworksGenome-Wide Association StudyHumans

Identifiers

PMID24707485
PMCPMC3953674

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.