ArticleCurrent breast cancer reports2013
Utility of GnRH-agonists for Fertility Preservation in Women With Operable Breast Cancer: Is It Protective?
Article in Current breast cancer reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 25 citations in OpenAlex.
- The Experience of Fertility Preservation in a Single Tertiary Center in Korea.Frontiers in endocrinology · 2022Article
- Artificial Ovary for Young Female Breast Cancer Patients.Frontiers in medicine · 2022Review
- The role of gonadotropin-releasing hormone agonists in female fertility preservation.Clinical and experimental reproductive medicine · 2021Article
- Case Report: Young Adults With Breast Cancer: A Case Series of Fertility Preservation Management and Literature Review.Frontiers in medicine · 2021Article
- Fertility Rates in Young Korean Breast Cancer Patients Treated with Gonadotropin-Releasing Hormone and Chemotherapy.Journal of breast cancer · 2017Article
- Premature ovarian insufficiency: from pathogenesis to clinical management.Journal of endocrinological investigation · 2015Review
- Dexrazoxane abrogates acute doxorubicin toxicity in marmoset ovary.Biology of reproduction · 2015Article
- Preserving fertility in patients undergoing treatment for breast cancer: current perspectives.Breast cancer (Dove Medical Press) · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Breast cancer is the most common type of malignancy in reproductive-age women. Breast cancer chemotherapy is associated with premature ovarian failure, infertility and negative psychosocial effects related to these reproductive changes. As a result of this, fertility preservation becomes highly critical in this group of women. Besides the fertility preservation methods that utilize assisted reproductive technologies such as embryo, oocyte, and ovarian tissue cryopreservation, another suggested strategy for fertility preservation is suppression of ovarian ovulatory function by gonadotropin-releasing hormone agonist (GnRHa) administration before and during chemotherapy. However, both the efficacy and safety of GnRH agonists for prevention of ovarian damage are unproven and the preponderance of evidence indicates that this is an ineffective strategy. This review details the most recent information and studies on this controversial topic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.