Evidence map›Paper›PMID 24707339›Full record

ArticleThe Neurohospitalist2014

Neurosarcoidosis: clinical review of a disorder with challenging inpatient presentations and diagnostic considerations.

J Chad Hoyle, Courtney Jablonski, Herbert B Newton

Abstract read
In one paragraph

Article in The Neurohospitalist, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
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  12. Off Trail, On Track: an Exercise in Clinical Reasoning.Journal of general internal medicine · 2019
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  15. Review
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  19. Observational
  20. The devil is in the detail: Acute Guillain-Barré syndrome camouflaged as neurosarcoidosis in a critically ill patient admitted to an Intensive Care Unit.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J Chad HoyleDepartment of Neurology, Wexner Medical Center, The Ohio State University, Columbus, OH, USA.
Courtney JablonskiDepartment of Internal Medicine, Wexner Medical Center and Nationwide Children's Hospital, The Ohio State University, Columbus, OH, USA ; Department of Pediatrics, Wexner Medical Center and Nationwide Children's Hospital, The Ohio State University, Columbus, OH, USA.
Herbert B NewtonDepartment of Neurology, Wexner Medical Center and James Cancer Hospital, The Ohio State University, Columbus, OH, USA ; Department of Neurosurgery, Wexner Medical Center and James Cancer Hospital, The Ohio State University, Columbus, OH, USA ; Department of Oncology, Wexner Medical Center and James Cancer Hospital, The Ohio State University, Columbus, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurosarcoidosis is frequently on the differential diagnosis for neurohospitalists. The diagnosis can be challenging due to the wide variety of clinical presentations as well as the limitations of noninvasive diagnostic testing. This article briefly touches on systemic features that may herald suspicion of this disorder and then expands in depth on the neurological clinical presentations. Common patterns of neurological presentations are reviewed and unusual presentations are also included. A discussion of noninvasive testing is undertaken, exploring dilemmas that may be encountered with sensitivity and specificity. Drawing from a broad range of clinical clues and diagnostic data, a systematic approach of pursuing a potential tissue diagnosis is then highlighted. Correctly diagnosing neurosarcoidosis is critical, as treatment with appropriate immunosuppression protocols can then be initiated. Additionally, treatment of refractory disease, the trend toward exploring targeted immunomodulation options, and other therapeutic issues are discussed.

Indexed as

autoimmune diseases of the nervous systemgeneral neurologyneurohospitalist

Identifiers

PMID24707339
PMCPMC3975794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.