SynthesisWorld journal of gastroenterology2014
Evidence based medicine and surgical approaches for colon cancer: evidences, benefits and limitations of the laparoscopic vs open resection.
Synthesis in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Laparoscopic appendicectomy is superior to open surgery for complicated appendicitis.Surgical endoscopy · 2019Pooled it
- Meta-analysis of short- and long-term outcomes after pure laparoscopic versus open liver surgery in hepatocellular carcinoma patients.Surgical endoscopy · 2019Pooled it
- What have we learned in minimally invasive colorectal surgery from NSQIP and NIS large databases? A systematic review.International journal of colorectal disease · 2018Pooled it
- Laparoscopic versus robotic-assisted colectomy and rectal resection: a systematic review and meta-analysis.International journal of colorectal disease · 2016Pooled it
- Is minimally invasive surgery safe and effective for pT4 colon cancer? Results from a national retrospective cohort study.Surgical endoscopy · 2026Article
- Efficacy and safety of reduced-port laparoscopic surgery versus conventional laparoscopic surgery for colorectal cancer.BMC cancer · 2025Article
- Immune microenvironment and lymph node yield in colorectal cancer.British journal of cancer · 2023Article
- A standardized stepwise approach to minimally invasive ileocolic anastomosis: Tips and tricks for laparoscopic and robotic surgery.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022Article
- Article
- Clinical efficacy and quality of life after transrectal natural orifice specimen extraction for the treatment of middle and upper rectal cancer.Journal of gastrointestinal oncology · 2020Article
- Impact of Minimal Invasive Robotic Surgery on Recovery From Postoperative Ileus and Postoperative Gastrointestinal Tract Dysfunction.American journal of biomedical science & research · 2020Article
- Complex abdominal wall hernias as a barrier to quality of life in cancer survivorsCanadian journal of surgery. Journal canadien de chirurgie · 2019Article
- Improved perioperative care is associated with improved long-term survival in colorectal cancer.International journal of colorectal disease · 2018Article
- Comparison of the short-term outcomes of reduced-port laparoscopic surgery and conventional multiport surgery in colon cancer: a propensity score matching analysis.Annals of surgical treatment and research · 2018Article
- Real-world cost-effectiveness of laparoscopy versus open colectomy for colon cancer: a nationwide population-based study.Surgical endoscopy · 2017Article
- Reduced port laparoscopic surgery for colon cancer is safe and feasible in terms of short-term outcomes: comparative study with conventional multiport laparoscopic surgery.Annals of surgical treatment and research · 2016Article
- Race/ethnicity and socio-economic differences in colorectal cancer surgery outcomes: analysis of the nationwide inpatient sample.BMC cancer · 2016Article
- Laparoscopic colorectal surgery: Current status and implementation of the latest technological innovations.World journal of gastroenterology · 2016Review
- Laparoscopic surgery: A qualified systematic review.World journal of methodology · 2015Article
- [Treatment reality with respect to laparoscopic surgery of colonic cancer in Germany].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo report a meta-analysis of the studies that compared the laparoscopic with the open approach for colon cancer resection.
methodsForty-seven manuscripts were reviewed, 33 of which employed for meta-analysis according to the PRISMA guidelines. The results were differentiated according to the study design (prospective randomized trials vs case-control series) and according to the tumor's location. Outcome measures included: (1) short-term results (operating times, blood losses, bowel function recovery, post-operative pain, return to the oral intake, complications and hospital stay); (2) oncological adequateness (number of nodes harvested in the surgical specimens); and (3) long-term results (including the survivals' rates and incidence of incisional hernias) and (4) costs.
resultsMeta-analysis of trials provided evidences in support of the laparoscopic procedures for a several short-term outcomes including: a lower blood loss, an earlier recovery of the bowel function, an earlier return to the oral intake, a shorter hospital stay and a lower morbidity rate. Opposite the operating time has been confirmed shorter in open surgery. The same trend has been reported investigating case-control series and cancer by sites, even though there are some concerns regarding the power of the studies in this latter field due to the small number of trials and the small sample of patients enrolled. The two approaches were comparable regarding the mean number of nodes harvested and long-term results, even though these variables were documented reviewing the literature but were not computable for meta-analysis. The analysis of the costs documented lower costs for the open surgery, however just few studies investigated the incidence of post-operative hernias.
conclusionLaparoscopy is superior for the majority of short-term results. Future studies should better differentiate these approaches on the basis of tumors' location and the post-operative hernias.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.