ReviewWorld journal of gastroenterology2014
Immunologic, metabolic and genetic factors in hepatitis C virus infection.
Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Chronic hepatitis C and the risk for atherosclerotic and cardiomyopathic heart disease.World journal of hepatology · 2025Review
- Article
- Low Dietary Betaine Intake Is Associated with Increased Blood Cholesterol in Mexican Subjects.Healthcare (Basel, Switzerland) · 2024Article
- Article
- Hepatitis C virus clearance and less liver damage in patients with high cholesterol, low-density lipoprotein cholesterol andWorld journal of gastroenterology · 2019Article
- Follicular helper T cell and memory B cell immunity in CHC patients.Journal of molecular medicine (Berlin, Germany) · 2019Article
- Early Detection of Liver Damage in Mexican Patients with Chronic Liver Disease.Journal of translational internal medicine · 2017Article
- CD36 genetic variation, fat intake and liver fibrosis in chronic hepatitis C virus infection.World journal of hepatology · 2016Article
- Need of righteous attitudes towards eradication of hepatitis C virus infection in Latin America.World journal of gastroenterology · 2016Article
- Article
- Genetic, metabolic and environmental factors involved in the development of liver cirrhosis in Mexico.World journal of gastroenterology · 2015Review
- Genomic medicine in gastroenterology: A new approach or a new specialty?World journal of gastroenterology · 2015Review
- Spontaneous hepatitis C viral clearance and hepatitis C chronic infection are associated with distinct cytokine profiles in Mexican patients.Memorias do Instituto Oswaldo Cruz · 2015Article
- Expression profile and kinetics of cytokines and chemokines in patients with chronic hepatitis C.International journal of clinical and experimental medicine · 2015Article
- Imbalance of regulatory T cells and T helper type 17 cells in patients with chronic hepatitis C.Immunology · 2014Article
- Lipid profile in cirrhotic patients and its relation to clinical outcome.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanisms that regulate disease progression during hepatitis C virus (HCV) infection and the response to treatment are not clearly identified. Numerous studies have demonstrated that a strong host immune response against HCV favors HCV clearance. In addition, genetic factors and metabolic machinery, particularly cholesterol modulation, are involved in HCV infection. It is likely that the interplay between all of these factors contributes to the outcome of HCV infection. In recent years, the world has experienced its largest epidemic of obesity. Mexico and the United States are the leading sufferers from this epidemic at the global level. Obesity is associated with the development of numerous pathologies including hypercholesterolemia which is one of the eight most important risk factors for mortality in Mexico. This may be related to the course of HCV infection in this population. Here, we focus on the urgent need to study the progression of HCV infection in relation to ethnic characteristics. Discoveries are discussed that hold promise in identifying immune, metabolic and genetic factors that, in conjunction, could be therapeutic targets or predictors of the progression of HCV infection.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.