ArticleJournal of physical therapy science2014
Skilled reach training influences brain recovery following intracerebral hemorrhage in rats.
Article in Journal of physical therapy science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04027049 (Biologic Mechanisms of Early Exercise After Intracerebral Hemorrhage), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Biologic Mechanisms of Early Exercise After Intracerebral Hemorrhage: a Pilot Randomized Controlled Trial of Cycle Ergometry
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Motor Rehabilitation Provides Modest Functional Benefits After Intracerebral Hemorrhage: a Systematic Review and Meta-Analysis of Translational Rehabilitation Studies.Translational stroke research · 2025Pooled it
- Post-stroke BDNF Concentration Changes Following Physical Exercise: A Systematic Review.Frontiers in neurology · 2018Review
- Understanding the Mechanisms of Recovery and/or Compensation following Injury.Neural plasticity · 2017Review
- Therapeutic physical exercise in neural injury: friend or foe?Journal of physical therapy science · 2015Review
- Modified constraint-induced movement therapy for clients with chronic stroke: interrupted time series (ITS) design.Journal of physical therapy science · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
[Purpose] The present study investigated how skilled reach training influences functional and neurological brain recovery via a rat model with intracerebral hemorrhage. [Subjects] Thirty rats with intracerebral hemorrhage were divided into 2 groups randomly: the control group (CON) that did not receive any treatment, and the experimental group (SRT) that received skilled reach training. [Methods] The experimental group was trained through skilled reaching training with the affected upper limb in 15-minute sessions administered 6 days per week for 4 weeks. [Results] In the behavioral test, the results showed that motor function was significantly improved in the skilled reach training group compared with the control group. In the neurological teat, the expression level of brain-derived neurotrophic factor (BDNF) was significantly increased in the skilled reach training group compared with the control group. [Conclusion] Skilled reach training is able to facilitate both the expression of neurotrophic factor in the motor cortex and motor function recovery following intracerebral hemorrhage.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.