Evidence map›Paper›PMID 24706104›Full record

ArticleEuropean radiology2014

Stiffness of the surrounding tissue of breast lesions evaluated by ultrasound elastography.

JianQiao Zhou, WeiWei Zhan, YiJie Dong, ZhiFang Yang, Chun Zhou

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Article in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

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0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Predicting lymph node metastasis in papillary thyroid carcinoma: radiomics using two types of ultrasound elastography.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

JianQiao ZhouDepartment of Ultrasound, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200025, China.
WeiWei Zhan
YiJie Dong
ZhiFang Yang
Chun Zhou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the stiffness of the surrounding tissue of breast lesions using the strain ratio assessment method by ultrasound (US) elastography.

methodsThis was an institutional ethics committee approved prospective study. A total of 127 breast lesions in 118 women (mean age 48.23 ± 14.32, range 20-90) were examined with conventional and elastographic US. The strain ratio assessment method was utilized to semi-quantitatively evaluate the stiffness of the breast lesions and the surrounding tissue.

resultsFifty-five lesions were malignant and 72 were benign. The strain ratio of the surrounding tissue was significantly higher in malignant cases (1.49 ± 0.67) than in benign ones (1.17 ± 0.44) (P = 0.001), and yielded an Az value of 0.669 in the diagnosis of breast lesions. There was a significant high positive correlation between the strain ratio of the lesion and the strain ratio of the surrounding tissue in the malignant group (r = 0.740, P < 0.001), and a significant moderate positive correlation in the benign group (r = 0.595, P < 0.001).

conclusionThe stiffness of the surrounding tissue of malignant breast lesions was higher than that of benign lesions. The strain ratio of the surrounding tissue and the lesions was significantly correlated, and has potential for breast lesion diagnosis. KEY POINTS: • Stiffness of the surrounding tissue of malignant breast lesions was increased. • Stiffness of the surrounding tissue correlated with stiffness of breast lesions. • Stiffness of the surrounding tissue has potential use in diagnosis of breast lesions.

Indexed as

AdultAgedAged, 80 and overBiopsy, Fine-NeedleBreastBreast DiseasesBreast NeoplasmsDiagnosis, DifferentialElasticityFemaleFollow-Up StudiesHumansMiddle AgedPregnancyProspective StudiesReproducibility of Results

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.