ReviewSkeletal radiology2014
Intraosseous hibernoma: characterization of five cases and literature review.
Review in Skeletal radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical, Radiological, and Pathological Features of Intraosseous Hibernoma: A Systematic Review of Case Reports and Case Series.Current oncology (Toronto, Ont.) · 2025Pooled it
- Test yourself answer: 38-year-old female with left hip pain.Skeletal radiology · 2026Article
- Intraosseous hibernoma mimicking sclerotic bone metastasis-a case report.Skeletal radiology · 2025Article
- Intraosseous Hibernoma: A Rare Entity in Orthopedics With Peculiar Radiological Features.Cureus · 2023Article
- Benign incidental do-not-touch bone lesions.The British journal of radiology · 2023Review
- Intraosseous hibernoma in the rib.Interdisciplinary cardiovascular and thoracic surgery · 2023Article
- Case report: Intraosseous hibernoma (IOH) mimics osseous metastasis: another rare pitfall in FDG-PET-CT.Frontiers in nuclear medicine · 2023Article
- Intraosseous hibernoma: Two case reports and a review of the literature.Radiology case reports · 2022Article
- Intraosseous hibernoma of the appendicular skeleton.Skeletal radiology · 2022Article
- Diagnosis of Intraosseous Hibernoma of an Appendicular Skeleton in an Adult - A Rare Case Report.Journal of orthopaedic case reports · 2022Article
- Intraosseous hibernoma: A metastatic mimicker to consider on the differential.Radiology case reports · 2020Article
- Article
- Spinal Intraosseous Hibernoma: A Case Report and Review of Literature.Taehan Yongsang Uihakhoe chi · 2020Article
- A 63-Year-Old Male with Cauda Equina Syndrome.Brain pathology (Zurich, Switzerland) · 2020Article
- Immunophenotypic expression of UCP1 in hibernoma and other adipose/non adipose soft tissue tumours.Clinical sarcoma research · 2019Article
- Intraosseous Hibernoma: A Rare and Unique Intraosseous Lesion.Journal of pathology and translational medicine · 2017Article
- Imaging review of lipomatous musculoskeletal lesions.SICOT-J · 2017Article
- Intraosseous hibernoma: a rare adipocytic bone tumour.Skeletal radiology · 2016Article
- Hibernoma--two patients with a rare lipoid soft-tissue tumour.BMC medical imaging · 2015Article
- Intraosseous hibernoma: case report and tumor characterization.BJR case reports · 2015Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe the imaging and histopathological findings and provide an overview of a recently described and rare cause of bone sclerosis. MATERIALS AND
methodsFive cases of intra-osseous hibernoma of bone that presented over the last year. The imaging and histopathology is reviewed.
resultsAll cases were identified in asymptomatic middle-aged to elderly adults as incidental findings with bone sclerosis in the axial skeleton. MRI showed lesions that were T1 hypointense to subcutaneous fat and hyperintense to skeletal muscle and one showed contrast enhancement. Glucose avidity was demonstrated on FDGPET in both cases tested and isotope bone scan performed in three cases showed strong positivity in two, but uptake was inconspicuous in one case.
conclusionsIntra-osseous hibernoma is a rare cause of sclerotic bone lesions, predominating in the axial skeleton of middle-aged and elderly adults. They have a non-aggressive appearance on CT and on MRI are T1 hypointense to subcutaneous fat and hyperintense to skeletal muscle. They are usually T2 hyperintense and may show peripheral contrast enhancement. They may show increased glucose avidity on FDGPET and may or may not be positive on isotope bone scans. We suspect that with ever-increasing use of a variety of imaging techniques, particularly in a setting of staging for malignant disease, more such cases will come to light. This diagnosis should be added to the differential diagnosis of sclerotic bone lesions.
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