ArticleMolecules (Basel, Switzerland)2014
Antioxidant and anticancer constituents from the leaves of Liriodendron tulipifera.
Article in Molecules (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
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- Lysicamine Reduces Protein Kinase B (AKT) Activation and Promotes Necrosis in Anaplastic Thyroid Cancer.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Four Undescribed Pyranones from theMolecules (Basel, Switzerland) · 2023Article
- In Vitro, In Silico, and In Vivo Studies ofACS omega · 2023Article
- Screening the PRISM Library againstACS omega · 2022Article
- Phytochemical Analysis and Dermo-Cosmetic Evaluation ofAntioxidants (Basel, Switzerland) · 2021Article
- Constituents from the Fruiting Bodies ofMolecules (Basel, Switzerland) · 2021Article
- Chemical Constituents of the Leaves ofPlants (Basel, Switzerland) · 2021Article
- Exploring new applications of tulip tree (Liriodendron tulipifera L.): leaf essential oil as apoptotic agent for human glioblastoma.Environmental science and pollution research international · 2019Article
- The Phytochemistry of Cherokee Aromatic Medicinal Plants.Medicines (Basel, Switzerland) · 2018Review
- Biofunctional Constituents from Michelia compressa var. lanyuensis with Anti-Melanogenic Properties.Molecules (Basel, Switzerland) · 2015Article
- Gastroprotective efficacy and safety evaluation of scoparone derivatives on experimentally induced gastric lesions in rodents.Nutrients · 2015Article
- 2-Oxoglutarate-dependent dioxygenases in the biosynthesis of simple coumarins.Frontiers in plant science · 2014Review
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Authors and funding
4 authors.
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Abstract
Sixteen compounds were extracted and purified from the leaves of Liriodendron tulipifera. These compounds include aporphines, oxoaporphine, coumarin, sesquiterpene lactone, benzenoids, cyclitol and steroids. (+)-Norstephalagine (2) (an aporphine) and scopoletin (8) (a coumarin) were isolated from Liriodendron tulipifera leaves from the first time. The identified compounds were screened for their antiradical scavenging, metal chelating and ferric reducing power activities. The results have showed that these compounds have antioxidative activity. The study has also examined the chemopreventive property of the isolated compounds against human melanoma cells A375. The results shown that (-)-anonaine (1), (-)-liridinine (3), (+)-lirinidine (6), lysicamine (7) and epitulipinolide diepoxide (9) significantly inhibited the proliferation of melanoma cells. These results revealed that these compounds have antioxidative activity and chemopreventive activity in skin melanoma cells.
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