Evidence map›Paper›PMID 24705498›Full record

ArticleMolecular systems biology2014

The three most important things about origins: location, location, location.

Nicholas Rhind

Abstract readComment
In one paragraph

Article in Molecular systems biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Nicholas RhindBiochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA.

Funding

The Regulation of DNA Replication KineticsR01GM098815 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RHIND, NICHOLAS R · 2012 to 2015
$1.3M
NIGMS NIH HHS R01 GM098815
6 · The paper itself

Abstract

The reasons why some DNA replication origins fire earlier than others have remained elusive. New work by Gindin et al suggests that the distribution of replication origins, not their timing per se, is the major determinant of the timing of genome replication in human cells.

Indexed as

ChromatinDNA ReplicationDNA Replication TimingHumansChromatin

Identifiers

PMID24705498
PMCPMC4023393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.