Evidence map›Paper›PMID 24705146›Full record

ReviewSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

Advances in the diagnosis and management of inflammatory bowel disease: challenges and uncertainties.

Mahmoud Mosli, Mohammad Al Beshir, Bandar Al-Judaibi, Turki Al-Ameel, Abdulaziz Saleem, Talat Bessissow, Subrata Ghosh, Majid Almadi

Abstract readReview
In one paragraph

Review in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Engineered Tissue Models to Decode Host-Microbiota Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mahmoud MosliDepartment of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada, .
Mohammad Al Beshir
Bandar Al-Judaibi
Turki Al-Ameel
Abdulaziz Saleem
Talat Bessissow
Subrata Ghosh
Majid Almadi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past two decades, several advances have been made in the management of patients with inflammatory bowel disease (IBD) from both evaluative and therapeutic perspectives. This review discusses the medical advancements that have recently been made as the standard of care for managing patients with ulcerative colitis (UC) and Crohn's Disease (CD) and to identify the challenges associated with implementing their use in clinical practice. A comprehensive literature search of the major databases (PubMed and Embase) was conducted for all recent scientific papers (1990-2013) giving the recent updates on the management of IBD and the data were extracted. The reported advancements in managing IBD range from diagnostic and evaluative tools, such as genetic tests, biochemical surrogate markers of activity, endoscopic techniques, and radiological modalities, to therapeutic advances, which encompass medical, endoscopic, and surgical interventions. There are limited studies addressing the cost-effectiveness and the impact that these advances have had on medical practice. The majority of the advances developed for managing IBD, while considered instrumental by some IBD experts in improving patient care, have questionable applications due to constraints of cost, lack of availability, and most importantly, insufficient evidence that supports their role in improving important long-term health-related outcomes.

Indexed as

Standard of CareAntibodies, Monoclonal, HumanizedBiomarkersCapsule EndoscopyCell Migration InhibitionColitis, UlcerativeColonic PouchesCrohn DiseaseDiagnosis, DifferentialFecesHumansIntestine, SmallLactoferrinMagnetic Resonance ImagingNatalizumabSensitivity and SpecificityAntibodies, Monoclonal, HumanizedBiomarkersLactoferrinNatalizumab

Identifiers

PMID24705146
PMCPMC3987157

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.