ArticleVirulence2014
Porphyromonas gingivalis in periodontal pockets and heart valves.
Article in Virulence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Article
- Association of Periodontal Status and Porphyromonas gingivalis Concentration with Severity of Coronary Artery Disease in Angiography Patients.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Impact of increasedJournal of oral microbiology · 2025Article
- Exploring links between oral health and infective endocarditis.Frontiers in oral health · 2024Review
- Estimation of gingival crevicular fluid oxidative stress markers in school-aged children and teenagers with insufficient sleep.BMC oral health · 2022Article
- Porphyromonas gingivalis Virulence Factors and Clinical Significance in Periodontal Disease and Coronary Artery DiseasesPathogens (Basel, Switzerland) · 2022Review
- PAMPs and DAMPs as the Bridge Between Periodontitis and Atherosclerosis: The Potential Therapeutic Targets.Frontiers in cell and developmental biology · 2022Review
- Periodontal disease and influence of periodontal treatment on disease activity in patients with rheumatoid arthritis and spondyloarthritis.Rheumatology international · 2020Article
- Bacterial DNA detected on pathologically changed heart valves using 16S rRNA gene amplification.Folia microbiologica · 2018Article
- Prior oral conditions in patients undergoing heart valve surgery.Journal of clinical and experimental dentistry · 2017Article
- Periodontal inflamed surface area as a novel numerical variable describing periodontal conditions.Journal of periodontal & implant science · 2017Article
- Porphyromonas gingivalis: a heartful oral pathogen?Virulence · 2014Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is evidence that advanced infectious chronic periodontal inflammatory disease may have an impact on general health including cardiovascular diseases. The aim of this clinical study was to evaluate the ability of Porphyromonas gingivalis to colonize heart valves and, subsequently, to assess whether there is an association between the presence of the DNA of Porphyromonas gingivalis in periodontal pockets and in degenerated heart valves. MATERIALS AND
methodsThirty patients were enrolled in the study and 31 valve specimens harvested during cardiac surgery operations were examined. All patients underwent a periodontal examination. To evaluate the periodontal status of the patients the following clinical parameters were recorded: the pocket depth, bleeding on probing (BOP) and aproximal plaque index (API). The presence of P. gingivalis in heart valve specimens and samples from periodontal pockets was analyzed using a single-step PCR method.
resultsP. gingivalis DNA was detected in periodontal pockets of 15 patients (50%). However, the DNA of this periopathogen was found neither in the aortic nor in the mitral valve specimens.
conclusionsThis study suggests that P. gingivalis may not have an influence on the development of the degeneration of aortic and mitral valves.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.