ArticlePlant signaling & behavior2014
Rice nicotianamine synthase localizes to particular vesicles for proper function.
Article in Plant signaling & behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Identification of the Nicotianamine synthase (NAS) gene family in wheat (Triticum aestivum L.) and the role of its member TaNAS4-A in Zn and Fe transport.Functional & integrative genomics · 2025Article
- Barriers and carriers for transition metal homeostasis in plants.Plant communications · 2025Review
- Nicotianamine: A Key Player in Metal Homeostasis and Hyperaccumulation in Plants.International journal of molecular sciences · 2023Review
- Vesicle trafficking in rice: too little is known.Frontiers in plant science · 2023Review
- Genome-wide analysis of the NAAT, DMAS, TOM, and ENA gene families in maize suggests their roles in mediating iron homeostasis.BMC plant biology · 2022Article
- Genome-Wide Association Analysis Reveals the Genetic Basis of Iron-Deficiency Stress Tolerance in Maize.Frontiers in plant science · 2022Article
- Low-molecular-weight ligands in plants: role in metal homeostasis and hyperaccumulation.Photosynthesis research · 2021Review
- Potential Implications of Interactions between Fe and S on Cereal Fe Biofortification.International journal of molecular sciences · 2020Review
- Characterization of the Nicotianamine Exporter ENA1 in Rice.Frontiers in plant science · 2019Article
- Systemic Upregulation of MTP2- and HMA2-Mediated Zn Partitioning to the Shoot Supplements Local Zn Deficiency Responses.The Plant cell · 2018Article
- Investigation of Baseline Iron Levels in Australian Chickpea and Evaluation of a Transgenic Biofortification Approach.Frontiers in plant science · 2018Article
- The Nicotianamine Synthase Gene Is a Useful Candidate for Improving the Nutritional Qualities and Fe-Deficiency Tolerance of Various Crops.Frontiers in plant science · 2018Review
- Paralogs and mutants show that one DMA synthase functions in iron homeostasis in rice.Journal of experimental botany · 2017Article
- Regulating Subcellular Metal Homeostasis: The Key to Crop Improvement.Frontiers in plant science · 2016Review
- Iron deficiency regulated OsOPT7 is essential for iron homeostasis in rice.Plant molecular biology · 2015Article
- Transcriptomic analysis of rice in response to iron deficiency and excess.Rice (New York, N.Y.) · 2014Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Graminaceous plants release mugineic acid family phytosiderophores to acquire iron from the soil. Recently, we reported that particular vesicles are involved in deoxymugineic acid (DMA) and nicotianamine (NA) biosynthesis and in DMA secretion from rice roots. A fusion protein of rice NA synthase 2 (OsNAS2) and synthetic green fluorescent protein (sGFP) was observed in a dot-like pattern, moving dynamically within the cell. OsNAS2 mutated in the tyrosine motif or di-leucine motif, which was reported to be involved in cellular transport, caused a disruption in vesicular movement and vesicular localization, respectively. Unlike OsNAS2, Arabidopsis NA synthases AtNAS1-4 were distributed uniformly in the cytoplasm with no localization in dot-like structures when transiently expressed in tobacco BY-2 cells. Interestingly, Fe deficiency-inducible genes were upregulated in the OsNAS2-sGFP plants, and the amounts of NA and DMA produced and DMA secreted by the OsNAS2-sGFP plants were significantly higher than in those by the non-transformants and domain-mutated lines. We propose a model for OsNAS2-localized vesicles in rice, and discuss why the introduction of OsNAS2-sGFP caused a disturbance in Fe homeostasis.
Indexed as
Identifiers
24704865PMC4091187W1963728394What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.