Evidence map›Paper›PMID 24704795›Full record

ReviewNeurochemistry international2014

Drosophila melanogaster as a genetic model system to study neurotransmitter transporters.

Ciara A Martin, David E Krantz

Abstract readReview
In one paragraph

Review in Neurochemistry international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Connectomic analysis of taste circuits inbioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Microdosing ketamine inbioRxiv : the preprint server for biology · 2023
    Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Towards early detection of neurodegenerative diseases: A gut feeling.Frontiers in cell and developmental biology · 2023
    Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ciara A MartinUCLA Interdepartmental Program in Molecular Toxicology, United States.
David E KrantzDepartment of Psychiatry and Biobehavioral Sciences and Semel Institute for Neuroscience and Human Behavior, Hatos Center for Neuropharmacology, David Geffen School of Medicine University of California, Los Angeles, CA 90095, United States. Electronic address: dkrantz@ucla.edu.

Funding

Project 4: Pesticides and Genes In PD: Studies In HumansP01ES016732 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RITZ, BEATE R. · 2008 to 2012
$6.7M
Training in Molecular ToxicologyT32ES015457 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ALLARD, PATRICK, HANKINSON, OLIVER NMN · 2008 to 2025
$4.0M
Environmental toxin interactions with genetic risks for Parkinson's diseaseR01ES015747 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KRANTZ, DAVID EVAN · 2007 to 2011
$2.1M
Trafficking of the Drosophila Vesicular Monoamine TransporterR01MH076900 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KRANTZ, DAVID EVAN · 2007 to 2011
$1.5M
NIEHS NIH HHS P01 ES016732NIEHS NIH HHS R01 ES015747NIEHS NIH HHS T32 ES015457NIMH NIH HHS R01 MH076900
6 · The paper itself

Abstract

The model genetic organism Drosophila melanogaster, commonly known as the fruit fly, uses many of the same neurotransmitters as mammals and very similar mechanisms of neurotransmitter storage, release and recycling. This system offers a variety of powerful molecular-genetic methods for the study of transporters, many of which would be difficult in mammalian models. We review here progress made using Drosophila to understand the function and regulation of neurotransmitter transporters and discuss future directions for its use.

Indexed as

AnimalsCell MembraneDrosophila melanogasterDrosophila ProteinsHumansNeurotransmitter Transport ProteinsVesicular Neurotransmitter Transport ProteinsDrosophila ProteinsNeurotransmitter Transport ProteinsVesicular Neurotransmitter Transport ProteinsAcetylcholineChT1DATDopamineDrosophilaEAATGABAGATGlutamateInebriatedNeurotransmitter transporterOctopaminePortabellaSerotoninSERTSLC1SLC17SLC18SLC6VAChTVesicular transporterVGATVGLUTVMATVNUT

Identifiers

PMID24704795
PMCPMC4264877

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.