Evidence map›Paper›PMID 24704091›Full record

ArticleJournal of the American Academy of Dermatology2014

Incidence of bullous pemphigoid and mortality of patients with bullous pemphigoid in Olmsted County, Minnesota, 1960 through 2009.

Katherine E Brick, Chad H Weaver, Christine M Lohse, Mark R Pittelkow, Julia S Lehman, Michael J Camilleri, Mustafa Al-Hashimi, Carilyn N Wieland

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Academy of Dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 120 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Adjuvant therapy of severe and/or refractory bullous pemphigoid with immunoadsorption - A prospective monocenter pilot study.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Trial
  4. [New treatment options for autoimmune bullous diseases].Dermatologie (Heidelberg, Germany) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Katherine E BrickDepartment of Dermatology, Mayo Clinic, Rochester, Minnesota.
Chad H WeaverDepartment of Dermatology, Mayo Clinic, Rochester, Minnesota.
Christine M LohseDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota.
Mark R PittelkowDepartment of Dermatology, Mayo Clinic, Rochester, Minnesota; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota.
Julia S LehmanDepartment of Dermatology, Mayo Clinic, Rochester, Minnesota; Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota.
Michael J CamilleriDepartment of Dermatology, Mayo Clinic, Rochester, Minnesota; Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota.
Mustafa Al-HashimiDepartment of Dermatology, Mayo Clinic, Rochester, Minnesota.
Carilyn N WielandDepartment of Dermatology, Mayo Clinic, Rochester, Minnesota; Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota. Electronic address: wieland.carilyn@mayo.edu.
Mayo Clinic · US

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
NIA NIH HHS R01 AG034676
6 · The paper itself

Abstract

backgroundBullous pemphigoid (BP) is an autoimmune blistering disease that is associated with increased mortality.

objectiveWe sought to determine the incidence and mortality of patients with BP.

methodsA total of 87 residents of Olmsted County, Minnesota, were identified who had their first lifetime diagnosis of BP from January 1960 through December 2009. Incidence and mortality were compared with age- and sex-matched control patients from the same geographic area.

resultsThe adjusted incidence of BP was 2.4 per 100,000 person-years (95% confidence interval, 1.9-2.9). Incidence of BP increased significantly with age (P < .001) and over time (P = .034). Trend tests indicate increased diagnosis of localized disease (P = .006) may be a contributing factor. Survival observed in the incident BP cohort was significantly poorer than expected (P < .001). Survival was not different among patients with multisite versus localized disease (P = .90). LIMITATIONS: Retrospective study design and study population from a small geographic area are limitations.

conclusionIncidence of BP in the United States is comparable with that found in Europe and Asia. The mortality of BP is lower in the United States than Europe, but higher than previous estimates.

Indexed as

AdultAgedAged, 80 and overFemaleHumansIncidenceMaleMiddle AgedMinnesotaPemphigoid, BullousRetrospective StudiesSurvival Analysisautoimmune blistering disorderbullous pemphigoidepidemiologygeriatricincidencemortality

Identifiers

PMID24704091
PMCPMC4324601
OpenAlexW2162560453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.