ArticleTrends in immunology2014
Transcriptional regulation in the immune system: a status report.
Article in Trends in immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- PRDM Family Proteins in Immune Regulation: Epigenetic Control and Implications in Immune-Related Diseases.Biology · 2026Review
- Inhibition of RBPJ transcription complex promotes IL-17 and IFN-γ secretion by CD4⁺ T cells in hepatocellular carcinoma.Archives of pharmacal research · 2025Article
- Tissue-specific atlas of trans-models for gene regulation elucidates complex regulation patterns.BMC genomics · 2024Article
- Transcription factor defects in inborn errors of immunity with atopy.Frontiers in allergy · 2023Review
- Genetic architecture of innate and adaptive immune cells in pigs.Frontiers in immunology · 2023Article
- Decoding the spatial chromatin organization and dynamic epigenetic landscapes of macrophage cells during differentiation and immune activation.Nature communications · 2022Article
- Tissue-Specific Variations in Transcription Factors Elucidate Complex Immune System Regulation.Genes · 2022Article
- NF-κB Rel subunit exchange on a physiological timescale.Protein science : a publication of the Protein Society · 2021Article
- Fasting-induced FOXO4 blunts human CD4Nature metabolism · 2021Article
- Targeted Transcriptomics of Frog Virus 3 in Infected Frog Tissues Reveal Non-Coding Regulatory Elements and microRNAs in the Ranaviral Genome and Their Potential Interaction with Host Immune Response.Frontiers in immunology · 2021Article
- Methylation Pattern of the SOCS3 and IL6R Promoters in Rheumatoid Arthritis.International journal of inflammation · 2020Article
- BioTarget: A Computational Framework Identifying Cancer Type Specific Transcriptional Targets of Immune Response Pathways.Scientific reports · 2019Article
- A rapid and robust method for single cell chromatin accessibility profiling.Nature communications · 2018Article
- The Human Transcription Factors.Cell · 2018Review
- Epigenetic and transcriptional control of mast cell responses.F1000Research · 2017Review
- Transcriptional (ChIP-Chip) Analysis of ELF1, ETS2, RUNX1 and STAT5 in Human Abdominal Aortic Aneurysm.International journal of molecular sciences · 2015Article
- Temporal phenotypic features distinguish polarized macrophages in vitro.Autoimmunity · 2015Article
- Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment.eLife · 2014Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Regulated changes in transcription play a central role in virtually all events that accompany the development of the immune system and its response to microbial and environmental cues. Over the past 30 years, a large number of proteins that regulate transcription in the immune system have been discovered and much has been learned about their mechanisms of action. However, the field remains in its infancy, with technical challenges and the complexity of gene regulation circuitry limiting our current knowledge and providing formidable barriers to further advancement. Despite these barriers, the development of new and increasingly sophisticated technologies is speeding progress towards an understanding of the gene-specific and global logic through which transcription is regulated in key immunological settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.