Evidence map›Paper›PMID 24702995›Full record

ReviewCell stem cell2014

Stem cell imaging: from bench to bedside.

Patricia K Nguyen, Johannes Riegler, Joseph C Wu

Abstract readReview
In one paragraph

Review in Cell stem cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Future direction: molecular imaging-based stem cell research.European journal of nuclear medicine and molecular imaging · 2025
    Article
  5. Article
  6. Article
  7. Positron emission tomography probes for stem cell monitoring: a review.American journal of translational research · 2024
    Review
  8. Article
  9. Article
  10. An iPSC-derived exosome-pulsed dendritic cell vaccine boosts antitumor immunity in melanoma.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patricia K NguyenDepartment of Medicine, Division of Cardiology, Stanford, CA 94305, USA; Department of Radiology, Molecular Imaging Program, Stanford, CA 94305, USA; Stanford Cardiovascular Institute, Stanford, CA 94305, USA.
Johannes RieglerDepartment of Medicine, Division of Cardiology, Stanford, CA 94305, USA; Department of Radiology, Molecular Imaging Program, Stanford, CA 94305, USA; Stanford Cardiovascular Institute, Stanford, CA 94305, USA.
Joseph C WuDepartment of Medicine, Division of Cardiology, Stanford, CA 94305, USA; Department of Radiology, Molecular Imaging Program, Stanford, CA 94305, USA; Stanford Cardiovascular Institute, Stanford, CA 94305, USA; Institute of Stem Cell Biology and Regenerative Medicine, Stanford, CA 94305, USA. Electronic address: joewu@stanford.edu.

Funding

Molecular Imaging of Targeted Cardiac Gene TherapyR01HL093172 · NHLBI · STANFORD UNIVERSITY · PI WU, JOSEPH C. · 2009 to 2015
$2.7M
Integrated Strategies for Novel Treatment of Myocardial IschemiaR01HL095571 · NHLBI · STANFORD UNIVERSITY · PI WU, JOSEPH C. · 2010 to 2014
$2.0M
Molecular Imaging of Cardiac Stem Cell TherapyR01EB009689 · NIBIB · STANFORD UNIVERSITY · PI WU, JOSEPH C. · 2010 to 2013
$1.4M
NHLBI NIH HHS NIH HL093172NHLBI NIH HHS NIH HL095571NHLBI NIH HHS R01 HL093172NHLBI NIH HHS R01 HL095571NIBIB NIH HHS NIH EB009689NIBIB NIH HHS R01 EB009689
6 · The paper itself

Abstract

Although cellular therapies hold great promise for the treatment of human disease, results from several initial clinical trials have not shown a level of efficacy required for their use as a first line therapy. Here we discuss how in vivo molecular imaging has helped identify barriers to clinical translation and potential strategies that may contribute to successful transplantation and improved outcomes, with a focus on cardiovascular and neurological diseases. We conclude with a perspective on the future role of molecular imaging in defining safety and efficacy for clinical implementation of stem cell therapies.

Indexed as

Cell- and Tissue-Based TherapyMolecular ImagingStem Cell TransplantationCardiovascular DiseasesCell TrackingHumansNervous System DiseasesStem Cells

Identifiers

PMID24702995
PMCPMC4024441

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.