Evidence map›Paper›PMID 24702797›Full record

Trial reportJournal of the International AIDS Society2014

Families as catalysts for peer adherence support in enhancing hope for people living with HIV/AIDS in South Africa.

Caroline Masquillier, Edwin Wouters, Dimitri Mortelmans, Frederik le Roux Booysen

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International AIDS Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Caroline MasquillierDepartment of Sociology, Research Centre for Longitudinal and Life Course Studies (CELLO), University of Antwerp, Antwerp, Belgium; caroline.masquillier@ua.ac.be.
Edwin WoutersDepartment of Sociology, Research Centre for Longitudinal and Life Course Studies (CELLO), University of Antwerp, Antwerp, Belgium; Centre for Health Systems Research and Development, University of the Free State, Bloemfontein, South Africa.
Dimitri MortelmansDepartment of Sociology, Research Centre for Longitudinal and Life Course Studies (CELLO), University of Antwerp, Antwerp, Belgium.
Frederik le Roux BooysenDepartment of Economics, University of the Free State, Bloemfontein, South Africa.
University of Antwerp · BEUniversity of the Free State · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHope is an essential dimension of successful coping in the context of illnesses such as HIV/AIDS, because positive expectations for the future alleviate emotional distress, enhance quality of life and have been linked to the capacity for behavioural change. The social environment (e.g. family, peers) is a regulator of hope for people living with HIV/AIDS (PLWHA). In this regard, the dual aim of this article is (1) to analyze the influence of a peer adherence support (PAS) intervention and the family environment on the state of hope in PLWHA and (2) to investigate the interrelationship between the two determinants.

methodsThe Effective AIDS Treatment and Support in the Free State study is a prospective randomized controlled trial. Participants were recruited from 12 public antiretroviral treatment (ART) clinics across five districts in the Free State Province of South Africa. Each of these patients was assigned to one of the following groups: a control group receiving standard care, a group receiving additional biweekly PAS or a group receiving PAS and nutritional support. Latent cross-lagged modelling (Mplus) was used to analyse the impact of PAS and the family environment on the level of hope in PLWHA.

resultsThe results of the study indicate that neither PAS nor the family environment has a direct effect on the level of hope in PLWHA. Subsequent analysis reveals a positive significant interaction between family functioning and PAS at the second follow-up, indicating that better family functioning increases the positive effect of PAS on the state of hope in PLWHA.

conclusionsThe interplay between well-functioning families and external PAS generates higher levels of hope, which is an essential dimension in the success of lifelong treatment. This study provides additional insight into the important role played by family dynamics in HIV/AIDS care, and it underscores the need for PAS interventions that are sensitive to the contexts in which they are implemented.

Indexed as

HopePeer GroupSelf-Help GroupsAnti-HIV AgentsFamilyHIV InfectionsHumansSocial EnvironmentSouth AfricaAnti-HIV Agentsfamily functioninghopelatent cross-lagged modellingpeer adherence supportrandomized controlled trialSouth Africa

Identifiers

PMID24702797
PMCPMC3976531
OpenAlexW1977690899

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.