Evidence map›Paper›PMID 24702164›Full record

ArticleAntioxidants & redox signaling2014

Ionizing radiation: mechanisms and therapeutics.

Cristina M Furdui

Abstract readEditorial
In one paragraph

Article in Antioxidants & redox signaling, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Application of nano-radiosensitizers in combination cancer therapy.Bioengineering & translational medicine · 2023
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Cristina M FurduiSection on Molecular Medicine, Department of Internal Medicine, Wake Forest School of Medicine , Winston-Salem, North Carolina.

Funding

Analysis of Redox Modulated Signaling Networks in Response to Ionizing RadiationR01CA136810 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI FURDUI, CRISTINA MARIA · 2009 to 2013
$1.5M
NCI NIH HHS R01 CA136810
6 · The paper itself

Abstract

While chemotherapy and radiation therapy have been integral components of cancer management for decades, the issues of local recurrence, clinical resistance, and toxicities resulting from these treatment modalities have increased the interest in novel therapeutic approaches that could attenuate tumor progression and prevent recurrences. This Forum highlights current research focused on elucidation of the mechanisms of response to radiation treatment and the development of out-of-the-box therapeutic strategies for cancer treatment with radiation. Experts in the field of radiation research contribute with review articles describing the current knowledge on DNA damage response mechanisms, regulation of signaling involved in the DNA damage response by miRNA, the function of tumor hypoxia in tumor response to radiation, and the role of stem cells in protection of normal tissue against radiation damage.

Indexed as

Cell HypoxiaDNA DamageHumansMicroRNAsNeoplasmsRadiation, IonizingSignal TransductionMicroRNAs

Identifiers

PMID24702164
PMCPMC4060773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.