ArticleJournal of clinical and diagnostic research : JCDR2014
Evaluation of Culture, Antigen Detection and Polymerase Chain Reaction for Detection of Vaginal Colonization of Group B Streptococcus (GBS) in Pregnant Women.
Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Enhanced identification of Group B streptococcus in infants with suspected meningitis in Ethiopia.PloS one · 2020Trial
- Highly Sensitive and Rapid Identification ofFrontiers in microbiology · 2020Article
- Comparison of Three Nucleic Acid Amplification Tests and Culture for Detection of Group BJournal of clinical microbiology · 2019Article
- High prevalence of Group B Streptococcus colonization among pregnant women in Amman, Jordan.BMC pregnancy and childbirth · 2019Article
- Is a positive Christie-Atkinson-Munch-Peterson (CAMP) test sensitive enough for the identification of Streptococcus agalactiae?BMC infectious diseases · 2019Article
- Diagnostic performance of direct latex agglutination, post-enrichment latex agglutination and culture methods in screening of group B streptococci in late pregnancy: a comparative study.Infection and drug resistance · 2019Article
- Comparison of qPCR and culture methods for group B Streptococcus colonization detection in pregnant women: evaluation of a new qPCR assay.BMC infectious diseases · 2018Article
- Multicenter clinical evaluation of the Xpert GBS LB assay for detection of group B Streptococcus in prenatal screening specimens.Journal of clinical microbiology · 2015Article
- Disease burden due to Group BTherapeutic advances in infectious diseaseReview
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveGroup B Streptococcal infection is an important cause of neonatal morbidity and mortality. Early detection of perinatal vagino-rectal (VR) carriage of Group B Streptococcus (GBS) is important in the management of newborn infections. The objective of the study was to evaluate Culture, antigen detection and Polymerase chain reaction for detection of GBS in Pregnant women. SETTINGS AND
designObservational descriptive study was done in a tertiary care hospital in Southern India. MATERIALS AND
methodsVR swabs were collected from 50 women at 35 to 37 weeks of gestation. Culture in a selective Lim enrichment broth with subsequent culture on 5% sheep blood agar, Conventional PCR assay and antigen detection method were performed. The performance of antigen detection and PCR methods were compared with culture. STATISTICAL ANALYSIS: STATISTICAL ANALYSIS was performed by Chi-Square test.
resultsGBS cultures were positive for 16% of the specimen (8 out of 50). Considering culture as a gold standard, Sensitivity, Specificity, Positive predictive value and Negative predictive value of antigen detection was 100%, 92.86%, 72.73%, 100% and similarly for that of PCR was 100%, 45.23%, 25.80%, 100%, respectively.
conclusionAntigen detection method was the rapid, sensitive and specific test for the detection of GBS colonizers during pregnancy.
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