ArticleIndian journal of endocrinology and metabolism2014
Arterial stiffness in obese children: Role of adiposity and physical activity.
Article in Indian journal of endocrinology and metabolism, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Prevalence and factors associated with ultrasound-detected hepatopathy in Indian adolescents with type 1 Diabetes Mellitus.Endocrine · 2026Article
- Bone mineral density in children and adolescents with type 1 diabetes: A case-control study from South India.Journal of family medicine and primary care · 2026Article
- Weight-adjusted waist index and mortality in diabetic retinopathy: a NHANES 1999-2018 cohort study.Diabetology & metabolic syndrome · 2025Article
- Effect of metformin adjunct therapy on cardiometabolic parameters in Indian adolescents with type 1 diabetes: a randomized controlled trial.Frontiers in clinical diabetes and healthcare · 2024Article
- Physical activity is associated with lower pulsatile stress but not carotid stiffness in children.Journal of human hypertension · 2022Article
- Identification of Adolescents with Adiposities and Elevated Blood Pressure and Implementation of Preventive Measures Warrants the Use of Multiple Clinical Assessment Tools.Journal of personalized medicine · 2021Article
- Association between Objectively Measured Physical Activity and Arterial Stiffness in Children with Congenital Heart Disease.Journal of clinical medicine · 2021Article
- Could arterial stiffness be early reversible target organ damage test in childhood hypertension?Anatolian journal of cardiology · 2021Article
- Is Stiffness Parameter β Useful for the Evaluation of Atherosclerosis?~ Its Clinical Implications, Limitations, and Future Perspectives ~.Journal of atherosclerosis and thrombosis · 2021Review
- Haemodynamics of Hypertension in Children.Current hypertension reports · 2020Review
- A cardiovascular disease risk factor in children with congenital heart disease: unmasking elevated waist circumference - a CHAMPS* study *CHAMPS: Children's Healthy-Heart Activity Monitoring Program in Saskatchewan.BMC cardiovascular disorders · 2020Article
- What Do We Know about Diet and Markers of Cardiovascular Health in Children: A Review.International journal of environmental research and public health · 2019Review
- Is arterial stiffening associated with adiposity, severity of obesity and other contemporary cardiometabolic markers in a community sample of adolescents with obesity in the UK?BMJ paediatrics open · 2017Article
- Bone Health Status in Indian Overweight/Obese Children.Indian journal of pediatrics · 2016Article
- Assessment of Vitamin D Status, its Determinants and Relationship with Bone Health in Indian Children and Young Adults with Type-1 Diabetes.Indian journal of endocrinology and metabolismArticle
- Sub-Clinical Peripheral Neuropathy in Indian Adolescents with Type 1 Diabetes: Estimation of Prevalence and Modifiable Risk Factors.Indian journal of endocrinology and metabolismArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore association of adiposity and physical activity with arterial stiffness and to propose optimal waist circumference cutoffs, corresponding to 90(th) percentile of NHANES (National Health and Nutrition Examination Survey) for Indian children and adolescents. MATERIALS AND
methodsData on weight, height, waist circumference, physical activity and right Carotid artery Intima-Media-Thickness (CIMT), pulse wave velocity (PWV), elasticity modulus (Ep), stiffness index(β), arterial compliance (AC) were assessed in 250 children (72 normal-weight and 178 overweight/obese) aged 6-17 years from Pune city, India. Body composition was measured using Dual energy X-ray absorptiometry.
resultsTotal, 37.1% normal-weight and 98.2% overweight/obese children had high adiposity (>95(th) body fat percentile). Positive association of PWV and Ep (r = 0.5) also β(r = 0.25) with BMI (Body Mass Index), waist circumference and body fat (P < 0.05) was observed. Physical activity was inversely associated with PWV (r =-0.2), β(r =-0.13), Ep (r =-0.12) and positively with AC (r = 0.12) (P < 0.05). PWV significantly increased with increasing body fat for each tertile of physical activity (P < 0.05). Regression analysis revealed waist circumference, BMI, body fat and physical activity as independent associates for PWV after adjusting for age (P < 0.05). The cutoff of waist circumference yielding sensitivity and specificity for predicting the risk of high PWV was (-0.43, -0.44) for boys and girls with sensitivity in boys (girls) of 78% (87%) and specificity in boys (girls) 51% (70%). The observed cutoffs are less than the NHANES-III cutoff values of waist circumference for 90(th) percentiles according to age and sex.
conclusionHigh adiposity and low physical activity are adversely related to arterial stiffness in Indian children.
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