ArticleIndian journal of endocrinology and metabolism2014
Serum thyroid stimulating hormone, total and free T4 during the neonatal period: Establishing regional reference intervals.
Article in Indian journal of endocrinology and metabolism, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Comment on "The Effects of Thyroid Hormone Levels on Patent Ductus Arteriosus Closure in Newborns".Medeniyet medical journal · 2023Article
- Thyroid abnormalities in children with Down syndrome at St. Paul's hospital millennium medical college, Ethiopia.Endocrinology, diabetes & metabolism · 2022Review
- Thyroid Stimulating Hormone, T3 and T4 Population-based Reference Range and Children Prevalence of Thyroid Dysfunction: First Report from South of Iran.Iranian journal of pathology · 2022Article
- Normative Data for Thyroid Stimulating Hormone for Screening of Congenital Hypothyroidism.Indian journal of pediatrics · 2018Article
- Nomogram-based evaluation of thyroid function in appropriate-for-gestational-age neonates in intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextCongenital hypothyroidism (CH), the most common etiology of preventable mental retardation in children, is estimated to be more prevalent among Asian population.
aimsSince thyroid function tests (TFTs) varied among different ages and geographical regions, in this study, the neonatal thyroid reference intervals in a healthy neonatal population is determined for the first time in Iran. SETTINGS AND
designA cross-sectional study performed on 246 healthy term newborns aged between 2 days and 1 month. MATERIALS AND
methodsBlood samples were obtained by venipuncture from all subjects. The median, 2.5(th), 5(th), 95(th), and 97.5(th) percentile of serum thyroid-stimulating hormone (TSH), as well as the total and free T4 were assessed among different age groups. STATISTICAL ANALYSIS USED: Predictive Analytics Software (PASW Statistics 18) was used for the analysis.
resultsSerum TSH, total and free T4 concentration peaked in 5(th) to 7(th) days of life, continued over 2 weeks, then decreased and started reaching to adult reference range. A significant negative correlation between age and serum concentration of TSH (P = 0.02), total T4 (P = 0.01) and free T4 (P = 0.01) was found.
conclusionThis study yielded fairly different values for TFTs compared compared values found in other countries and also different from values reported for laboratory kits we used. These differences were assumed to be due to variations in ethnicity, age, and laboratory methods used. Due to the lack of international standardization, conducting multicenter studies helps in making a more precise evaluation of thyroid status in neonates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.