Evidence map›Paper›PMID 24701367›Full record

ReviewISRN obesity2014

Obesity and surgical wound healing: a current review.

Yvonne N Pierpont, Trish Phuong Dinh, R Emerick Salas, Erika L Johnson, Terry G Wright, Martin C Robson, Wyatt G Payne

Registry-linked trialOpen access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ISRN obesity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05739214 (The Effect of Combined Red and Infrared Lasers on Histopathology Collagen Formation in Diabetic Foot Ulcer), which is not on this map. Cited by 214 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
214citing papers in PubMed, 11 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05739214 nacompletednot on this mapstarted 2022, after this paper: background citation

The Effect of Combined Red and Infrared Lasers on Histopathology Collagen Formation in Diabetic Foot Ulcer: a Randomized Controlled Trial

TypeinterventionalSponsorCairo UniversityRan2022 to 2023Enrolled45ConditionsDiabetic Foot, Wound Heal, Collagen DiseasesArmslaser therapy
3 · Its place in the literature

Who cites it

214 citing papers in PubMed, 11 syntheses or guidelines pooled it, 416 citations in OpenAlex.

  1. Pooled it
  2. Laparoscopic versus open repair for umbilical hernia: outcomes and complications.Hernia : the journal of hernias and abdominal wall surgery · 2026
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  8. The relation between surgical approaches for pelvic ring and acetabular fractures and postoperative complications: a systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Pooled it
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  11. Association Between Obesity and Wound Infection Following Colorectal Surgery: Systematic Review and Meta-Analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017
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  18. Evaluating the impact of body-mass index on short- and medium-term outcomes after lumbar endoscopic decompression surgery: a single‑surgeon, multi‑hospital cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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154 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yvonne N PierpontInstitute for Tissue Regeneration, Repair & Rehabilitation, Bay Pines VA Health Care System, Bay Pines, FL 33744, USA ; Division of Plastic Surgery, University of South Florida, Tampa, FL 33620, USA.
Trish Phuong DinhDivision of Plastic Surgery, University of South Florida, Tampa, FL 33620, USA.
R Emerick SalasInstitute for Tissue Regeneration, Repair & Rehabilitation, Bay Pines VA Health Care System, Bay Pines, FL 33744, USA ; Division of Plastic Surgery, University of South Florida, Tampa, FL 33620, USA.
Erika L JohnsonInstitute for Tissue Regeneration, Repair & Rehabilitation, Bay Pines VA Health Care System, Bay Pines, FL 33744, USA ; Division of Plastic Surgery, University of South Florida, Tampa, FL 33620, USA.
Terry G WrightInstitute for Tissue Regeneration, Repair & Rehabilitation, Bay Pines VA Health Care System, Bay Pines, FL 33744, USA ; Division of Plastic Surgery, University of South Florida, Tampa, FL 33620, USA.
Martin C RobsonDivision of Plastic Surgery, University of South Florida, Tampa, FL 33620, USA.
Wyatt G PayneInstitute for Tissue Regeneration, Repair & Rehabilitation, Bay Pines VA Health Care System, Bay Pines, FL 33744, USA ; Division of Plastic Surgery, University of South Florida, Tampa, FL 33620, USA.
University of South Florida · USBay Pines VA Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective. The correlation between obesity and deficient wound healing has long been established. This review examines the current literature on the mechanisms involved in obesity-related perioperative morbidity. Methods. A literature search was performed using Medline, PubMed, Cochrane Library, and Internet searches. Keywords used include obesity, wound healing, adipose healing, and bariatric and surgical complications. Results. Substantial evidence exists demonstrating that obesity is associated with a number of postoperative complications. Specifically in relation to wound healing, explanations include inherent anatomic features of adipose tissue, vascular insufficiencies, cellular and composition modifications, oxidative stress, alterations in immune mediators, and nutritional deficiencies. Most recently, advances made in the field of gene array have allowed researchers to determine a few plausible alterations and deficiencies in obese individuals that contribute to their increased risk of morbidity and mortality, especially wound complications. Conclusion. While the literature discusses how obesity may negatively affect health on various of medical fronts, there is yet to be a comprehensive study detailing all the mechanisms involved in obesity-related morbidities in their entirety. Improved knowledge and understanding of obesity-induced physiological, cellular, molecular, and chemical changes will facilitate better assessments of surgical risks and outcomes and create efficient treatment protocols for improved patient care of the obese patient population.

Identifiers

PMID24701367
PMCPMC3950544
OpenAlexW2052693008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.