Evidence map›Paper›PMID 24701355›Full record

ReviewISRN gastroenterology2014

Oral Cavity as an Extragastric Reservoir of Helicobacter pylori.

Arwa Al Sayed, Pradeep S Anand, Kavitha P Kamath, Shankargouda Patil, R S Preethanath, Sukumaran Anil

Open access · diamondAbstract readReview
In one paragraph

Review in ISRN gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. BeyondMedicina (Kaunas, Lithuania) · 2025
    Review
  6. Article
  7. Review
  8. Detection of Helicobacter Pylori in Nasal Polyps: An Epidemiological Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  9. The impact ofFrontiers in microbiology · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. PeerJ · 2021
    Article
  15. Review
  16. Dentists Are at a Higher Risk for OralBioMed research international · 2020
    Article
  17. Journal of periodontal & implant science · 2019
    Article
  18. Molecular detection ofJournal of dental sciences · 2019
    Article
  19. Article
  20. Helicobacter Pylori Infection and Lung Cancer: 
New Insights and Future Challenges.Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2018
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Arwa Al SayedDepartment of Dentistry, Prince Sultan Military Medical City, Ministry of Defense, P.O. Box 2993, Riyadh 11461, Saudi Arabia.ORCID 0000-0001-5403-7536
Pradeep S AnandDepartment of Periodontics, People's College of Dental Sciences & Research Centre, Bhopal, Madhya Pradesh 462037, India.
Kavitha P KamathDepartment of Oral Pathology, People's Dental Academy, Bhopal, Madhya Pradesh 462037, India.
Shankargouda PatilDepartment of Oral Pathology, MS Ramaiah Dental College and Hospital, Bangalore, Karnataka 560054, India.
R S PreethanathDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.
Sukumaran AnilDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.
King Saud University · SAPeople’s University · INM. S. Ramaiah Dental College and Hospital · INRiyadh Armed Forces Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background. Several studies were reported on the prevalence, and relationship between the existence of Helicobacter pylori (H. pylori) in oral cavity and in stomach of patients. The purpose of this study was to systematically review the existing literature on the presence of H. pylori in the oral cavity and its link to gastric infection, the existence of coinfection, and the impact of anti-H. pylori therapy on the dental plaque and vice versa. Method. Two authors independently searched the Medline, EMBASE, Cochrane Library, Web of Science, Google Scholar, and Scopus databases for relevant studies. The articles were analyzed critically and all qualified studies were included. The search was carried out by using a combined text and the MeSH search strategies: using the key words Helicobacter, Helicobacter pylori, and H. pylori in combination with dental plaque, periodontitis, and oral hygiene. Results. The data was presented in 8 tables and each topic separately discussed. Conclusion. Based on the systematic review of the available literature on H. pylori infection and its presence in the oral cavity, it can be concluded that dental plaque can act as a reservoir, and proper oral hygiene maintenance is essential to prevent reinfection. Due to the diversified methods and population groups involved in the available literature, no concrete evidence can be laid down. Further studies are necessary to establish the role of H. pylori in the oral cavity and its eradication on preventing the gastroduodenal infection.

Identifiers

PMID24701355
PMCPMC3950549
OpenAlexW2063441682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.