Evidence map›Paper›PMID 24701030›Full record

ArticleChemistry of materials : a publication of the American Chemical Society2014

Nano-photosensitizers Engineered to Generate a Tunable Mix of Reactive Oxygen Species, for Optimizing Photodynamic Therapy, Using a Microfluidic Device.

Hyung Ki Yoon, Xia Lou, Yu-Chih Chen, Yong-Eun Koo Lee, Euisik Yoon, Raoul Kopelman

Abstract read
In one paragraph

Article in Chemistry of materials : a publication of the American Chemical Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Au nanobipyramids@mSiONanoscale advances · 2020
    Article
  11. Article
  12. Review
  13. An In Vitro Approach to Photodynamic Therapy.Journal of visualized experiments : JoVE · 2018
    Article
  14. Article
  15. Article
  16. Article
  17. Lifetime-resolved Photoacoustic (LPA) Spectroscopy for monitoring Oxygen change and Photodynamic Therapy (PDT).Proceedings of SPIE--the International Society for Optical Engineering · 2016
    Article
  18. Intracellular Photodynamic Activity of Chlorin e6 Containing Nanoparticles.International journal of nanomedicine and nanosurgery · 2016
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hyung Ki YoonDepartment of Chemistry, University of Michigan, Ann Arbor, MI 48109, United States.
Xia LouDepartment of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, United States.
Yu-Chih ChenDepartment of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, United States.
Yong-Eun Koo LeeDepartment of Chemistry, University of Michigan, Ann Arbor, MI 48109, United States.
Euisik YoonDepartment of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, United States.
Raoul KopelmanDepartment of Chemistry, University of Michigan, Ann Arbor, MI 48109, United States.
University of Michigan–Ann Arbor · US

Funding

Nanoparticle Enabled Intraoperative Imaging and TherapyR01EB007977 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOPELMAN, RAOUL · 2007 to 2009
$2.8M
Nanobiophotonics Enabled Tumor Surgery and Intraoperative PDTR33CA125297 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOPELMAN, RAOUL · 2008 to 2010
$1.5M
NCI NIH HHS R33 CA125297NIBIB NIH HHS R01 EB007977
6 · The paper itself

Abstract

This work is aimed at engineering photosensitizer embedded nanoparticles (NPs) that produce optimal amount of reactive oxygen species (ROS) for photodynamic therapy (PDT). A revised synthetic approach, coupled with improved analytical tools, resulted in more efficient PDT. Specifically, methylene blue (MB) conjugated polyacrylamide nanoparticles (PAA NPs), with a polyethylene glycol dimethacrylate (PEGDMA, M

Indexed as

methylene bluemicrofluidic chipphotodynamic therapypolyacrylamide nanoparticlereactive oxygen species (ROS)

Identifiers

PMID24701030
PMCPMC3970790
OpenAlexW2327725770

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.