Evidence map›Paper›PMID 24700820›Full record

ArticleDevelopment (Cambridge, England)2014

A conserved axon type hierarchy governing peripheral nerve assembly.

Liang Wang, Alessandro Mongera, Dario Bonanomi, Lukas Cyganek, Samuel L Pfaff, Christiane Nüsslein-Volhard, Till Marquardt

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Mapping of Extrinsic Innervation of the Gastrointestinal Tract in the Mouse Embryo.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Evolution of the Marrow Adipose Tissue Microenvironment.Calcified tissue international · 2017
    Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liang WangDevelopmental Neurobiology Laboratory, European Neuroscience Institute (ENI-G), Grisebachstraße 5, Göttingen 37077, Germany.
Alessandro Mongera
Dario Bonanomi
Lukas Cyganek
Samuel L Pfaff
Christiane Nüsslein-Volhard
Till Marquardt

Funding

LIM GENE CONTROL OF MOTOR NEURON DEVELOPMENTR01NS037116 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI PFAFF, SAMUEL L. · 1997 to 2006
$3.4M
Proto-oncogenes in Axon GuidanceR01NS054172 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI PFAFF, SAMUEL L. · 2007 to 2011
$2.1M
NINDS NIH HHS R01 NS037116NINDS NIH HHS R01 NS054172
6 · The paper itself

Abstract

In gnathostome vertebrates, including fish, birds and mammals, peripheral nerves link nervous system, body and immediate environment by integrating efferent pathways controlling movement apparatus or organ function and afferent pathways underlying somatosensation. Several lines of evidence suggest that peripheral nerve assembly involves instructive interactions between efferent and afferent axon types, but conflicting findings challenge this view. Using genetic modeling in zebrafish, chick and mouse we uncover here a conserved hierarchy of axon type-dependent extension and selective fasciculation events that govern peripheral nerve assembly, which recapitulates the successive phylogenetic emergence of peripheral axon types and circuits in the vertebrate lineage.

Indexed as

AnimalsAxonsChick EmbryoChickensDermisMiceMotor NeuronsNeurons, AfferentNeurons, EfferentPeripheral NervesZebrafishAxon-axon interactionsAxon guidanceChickMotor neuronsMousePeripheral nerveSensory neuronsSympathetic neuronsZebrafish

Identifiers

PMID24700820
PMCPMC13148187

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.