Evidence map›Paper›PMID 24700712›Full record

ArticleBlood2014

STIM1 for stimulation of phagocyte NADPH oxidase.

Richard D Ye

Abstract readComment
In one paragraph

Article in Blood, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Richard D YeSHANGHAI JIAO TONG UNIVERSITY;

Funding

MOLECULAR MECHANISMS OF LEUKOCYTE ACTIVATIONR01AI033503 · NIAID · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YE, RICHARD D · 1993 to 2014
$4.5M
NIAID NIH HHS R01 AI033503
6 · The paper itself

Abstract

In this issue of Blood, Zhang et al show that mice lacking the stromal-interacting molecule 1 (STIM1) gene in bone marrow cells are more susceptible to bacterial infection but are resistant to ischemia/reperfusion injury because of defective activation of phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase.

Indexed as

AnimalsCalcium ChannelsImmunityInflammationMembrane GlycoproteinsOxidoreductasesPhagocytesStromal Interaction Molecule 1Calcium ChannelsMembrane GlycoproteinsOxidoreductasesStim1 protein, mouseStromal Interaction Molecule 1

Identifiers

PMID24700712
PMCPMC3975253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.