ArticleJournal of cellular biochemistry2014
Niche inheritance: a cooperative pathway to enhance cancer cell fitness through ecosystem engineering.
Article in Journal of cellular biochemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 50 citations in OpenAlex.
- Fisher Information Limits on Genetic Stability, Diversity, and Regulation.Bulletin of mathematical biology · 2026Article
- Selective sweep probabilities in spatially expanding populations.Nature communications · 2026Article
- A mechanovascular framework for pre-neoplastic microenvironmental dysregulation and early carcinogenesis.Frontiers in oncology · 2026Article
- Single-cell RNA-sequencing atlas reveals an FABP1-dependent immunosuppressive environment in hepatocellular carcinoma.Journal for immunotherapy of cancer · 2023Article
- Nasopharyngeal carcinoma ecology theory: cancer as multidimensional spatiotemporal "unity of ecology and evolution" pathological ecosystem.Theranostics · 2023Review
- Metformin promotes antitumor activity of NK cells via overexpression of miRNA-150 and miRNA-155.American journal of translational research · 2023Article
- Tumors Are Evolutionary Island-Like Ecosystems.Genome biology and evolution · 2021Article
- Review
- Variation in the life history strategy underlies functional diversity of tumors.National science review · 2021Article
- Oral and intestinal bacterial exotoxins: Potential linked to carcinogenesis.Progress in molecular biology and translational science · 2020Review
- Polyploid giant cancer cells: Unrecognized actuators of tumorigenesis, metastasis, and resistance.The Prostate · 2019Review
- Hepatic Tumor Microenvironments and Effects on NK Cell Phenotype and Function.International journal of molecular sciences · 2019Review
- Alterations of tumor microenvironment by nitric oxide impedes castration-resistant prostate cancer growth.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Epigenetic control of macrophage polarization: implications for targeting tumor-associated macrophages.Oncotarget · 2018Review
- Article
- Classifying the evolutionary and ecological features of neoplasms.Nature reviews. Cancer · 2017Review
- Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?Molecular oncology · 2017Review
- Revisiting Seed and Soil: Examining the Primary Tumor and Cancer Cell Foraging in Metastasis.Molecular cancer research : MCR · 2017Review
- Ecological paradigms to understand the dynamics of metastasis.Cancer letters · 2016Review
- Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype.Journal of the Royal Society, Interface · 2016Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Cancer cells can be described as an invasive species that is able to establish itself in a new environment. The concept of niche construction can be utilized to describe the process by which cancer cells terraform their environment, thereby engineering an ecosystem that promotes the genetic fitness of the species. Ecological dispersion theory can then be utilized to describe and model the steps and barriers involved in a successful diaspora as the cancer cells leave the original host organ and migrate to new host organs to successfully establish a new metastatic community. These ecological concepts can be further utilized to define new diagnostic and therapeutic areas for lethal cancers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.