ArticleMagnetic resonance in medicine2015
Susceptibility tensor imaging of the kidney and its microstructural underpinnings.
Article in Magnetic resonance in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Diffusion tractography outside the brain: the road less travelled.Brain structure & function · 2026Review
- Progress of functional magnetic resonance imaging in the assessment of transplanted kidney function.Renal failure · 2025Review
- Observations of anisotropic paramagnetic and diamagnetic susceptibility in the primate brain.bioRxiv : the preprint server for biology · 2025Article
- Hemosiderin quantification in hemophilic arthropathy using quantitative magnetic resonance imaging.Scientific reports · 2025Article
- Diffusion tractography of kidney by high angular resolution diffusion imaging.Magnetic resonance letters · 2024Article
- QSM Throughout the Body.Journal of magnetic resonance imaging : JMRI · 2023Review
- Quantitative susceptibility mapping of the head-and-neck using SMURF fat-water imaging with chemical shift and relaxation rate corrections.Magnetic resonance in medicine · 2022Article
- Alterations of Renal Function in Patients with Diabetic Kidney Disease: A BOLD and DTI Study.Computational intelligence and neuroscience · 2022Article
- Asymmetric susceptibility tensor imaging.Magnetic resonance in medicine · 2021Article
- Feasibility of quantitative susceptibility mapping (QSM) of the human kidney.Magma (New York, N.Y.) · 2021Article
- Mapping kidney tubule diameter ex vivo by diffusion MRI.American journal of physiology. Renal physiology · 2021Article
- New imaging tools to measure nephron numberJournal of developmental origins of health and disease · 2021Review
- Ultrashort echo time quantitative susceptibility mapping (UTE-QSM) for detection of hemosiderin deposition in hemophilic arthropathy: A feasibility study.Magnetic resonance in medicine · 2020Article
- Mapping vascular and glomerular pathology in a rabbit model of neonatal acute kidney injury using MRI.Anatomical record (Hoboken, N.J. : 2007) · 2020Article
- Non-invasive assessment of early stage diabetic nephropathy by DTI and BOLD MRI.The British journal of radiology · 2020Article
- Learning-based single-step quantitative susceptibility mapping reconstruction without brain extraction.NeuroImage · 2019Article
- High-resolution MRI of kidney microstructures at 7.05 T with an endo-colonic Wireless Amplified NMR detector.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2019Article
- Bone susceptibility mapping with MRI is an alternative and reliable biomarker of osteoporosis in postmenopausal women.European radiology · 2018Article
- Quantifying MRI frequency shifts due to structures with anisotropic magnetic susceptibility using pyrolytic graphite sheet.Scientific reports · 2018Article
- Investigating magnetic susceptibility of human knee joint at 7 Tesla.Magnetic resonance in medicine · 2017Article
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7 authors.
Funding
Abstract
purposeThe purpose of this study was to determine whether susceptibility tensor imaging (STI) could overcome limitations of current techniques to detect tubules throughout the kidney.
methodsNormal mouse kidneys (n = 4) were imaged at 9.4T using a three-dimensional gradient multi-echo sequence (55-micron isotropic resolution). Phase images from 12 orientations were obtained to compute the susceptibility tensor. Diffusion tensor imaging (DTI) with 12 encoding directions was compared with STI. Tractography was performed to visualize and track the course of tubules with DTI and STI. Confocal microscopy was used to identify which tubular segments of the nephron were detected by DTI and STI.
resultsDiffusion anisotropy was limited to the inner medulla of the kidney. DTI did not find a significant number of coherent tubular tracks in the outer medulla or cortex. With STI, we found strong susceptibility anisotropy and many tracks in the inner and outer medulla and in limited areas of the cortex.
conclusionSTI was able to track tubules throughout the kidney, whereas DTI was limited to the inner medulla. STI provides a novel contrast mechanism related to local tubule microstructure and may offer a powerful method to study the nephron.
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