Trial reportThe American journal of psychiatry2014
Internet-delivered treatment for substance abuse: a multisite randomized controlled trial.
Trial report in The American journal of psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 4 registered trials, which are not on this map. Cited by 159 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Treatment Engagement With Technology-assisted Treatment
UControlPain App (This is the Official IRB Title)
Efficiency And Quality In Post-Surgical Pain Therapy After Discharge
Substituting SMSs for Provider-delivered Care to Improve Alcohol Use Outcomes in People With and Without HIV in Lesotho
Who cites it
159 citing papers in PubMed, 10 syntheses or guidelines pooled it, 272 citations in OpenAlex.
- Digitally Delivered Cognitive Behavioral Interventions for Alcohol and Other Drug Use: Meta-Analysis Across Consumption and Psychosocial Outcomes.JMIR mental health · 2026Pooled it
- Prevalence of Dropout and Influencing Factors in Digital Psychosocial Intervention Trials for Adult Illicit Substance Users: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- How effective are remote and/or digital interventions as part of alcohol and drug treatment and recovery support? A systematic review and meta-analysis.Addiction (Abingdon, England) · 2025Pooled it
- Psychosocial interventions for stimulant use disorder.The Cochrane database of systematic reviews · 2024Pooled it
- Collection and Analysis of Adherence Information for Software as a Medical Device Clinical Trials: Systematic Review.JMIR mHealth and uHealth · 2023Pooled it
- Measures of Effectiveness, Efficiency, and Quality of Telemedicine in the Management of Alcohol Abuse, Addiction, and Rehabilitation: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Technology-Delivered Cognitive-Behavioral Interventions for Alcohol Use: A Meta-Analysis.Alcoholism, clinical and experimental research · 2019Pooled it
- Blending Face-to-Face and Internet-Based Interventions for the Treatment of Mental Disorders in Adults: Systematic Review.Journal of medical Internet research · 2017Pooled it
- Internet interventions for adult illicit substance users: a meta-analysis.Addiction (Abingdon, England) · 2017Pooled it
- The ASAM/AAAP Clinical Practice Guideline on the Management of Stimulant Use Disorder.Journal of addiction medicineGuideline
- A randomized controlled trial to assess whether a telehealth-based contingency management intervention reduces alcohol use for individuals with alcohol use disorder.Contemporary clinical trials · 2025Trial
- Predicting Long-Term Engagement in mHealth Apps: Comparative Study of Engagement Indices.Journal of medical Internet research · 2024Trial
- Culturally tailored digital therapeutic for substance use disorders with urban Indigenous people in the United States: A randomized controlled study.Journal of substance use and addiction treatment · 2023Trial
- Digital delivery of a contingency management intervention for substance use disorder: A feasibility study with DynamiCare Health.Journal of substance abuse treatment · 2021Trial
- Digital therapeutics for essential hypertension using a smartphone application: A randomized, open-label, multicenter pilot study.Journal of clinical hypertension (Greenwich, Conn.) · 2021Trial
- Internet-based therapy versus face-to-face therapy for alcohol use disorder, a randomized controlled non-inferiority trial.Addiction (Abingdon, England) · 2021Trial
- Feasibility and Preliminary Efficacy of a Community-Based Addiction Rehabilitation Electronic System in Substance Use Disorder: Pilot Randomized Controlled Trial.JMIR mHealth and uHealth · 2021Trial
- Generalizing randomized trial findings to a target population using complex survey population data.Statistics in medicine · 2021Trial
- Safety and efficacy of a prescription digital therapeutic as an adjunct to buprenorphine for treatment of opioid use disorder.Current medical research and opinion · 2021Trial
- Understanding site variability in a multisite clinical trial of a technology-delivered psychosocial intervention for substance use disorders.Journal of substance abuse treatment · 2019Trial
99 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issuedCorrection.2014
Authors and funding
17 authors at 1 institution in 1 country.
Funding
Abstract
objectiveComputer-delivered interventions have the potential to improve access to quality addiction treatment care. The objective of this study was to evaluate the effectiveness of the Therapeutic Education System (TES), an Internet-delivered behavioral intervention that includes motivational incentives, as a clinician-extender in the treatment of substance use disorders.
methodAdult men and women (N=507) entering 10 outpatient addiction treatment programs were randomly assigned to receive 12 weeks of either treatment as usual (N=252) or treatment as usual plus TES, with the intervention substituting for about 2 hours of standard care per week (N=255). TES consists of 62 computerized interactive modules covering skills for achieving and maintaining abstinence, plus prize-based motivational incentives contingent on abstinence and treatment adherence. Treatment as usual consisted of individual and group counseling at the participating programs. The primary outcome measures were abstinence from drugs and heavy drinking (measured by twice-weekly urine drug screens and self-report) and time to dropout from treatment.
resultsCompared with patients in the treatment-as-usual group, those in the TES group had a lower dropout rate (hazard ratio=0.72, 95% CI=0.57, 0.92) and a greater abstinence rate (odds ratio=1.62, 95% CI=1.12, 2.35). This effect was more pronounced among patients who had a positive urine drug or breath alcohol screen at study entry (N=228) (odds ratio=2.18, 95% CI=1.30, 3.68).
conclusionsInternet-delivered interventions such as TES have the potential to expand access and improve addiction treatment outcomes. Additional research is needed to assess effectiveness in non-specialty clinical settings and to differentiate the effects of the community reinforcement approach and contingency management components of TES.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.