Evidence map›Paper›PMID 24700296›Full record

ReviewAAPS PharmSciTech2014

Polymeric micelles: nanocarriers for cancer-targeted drug delivery.

Yifei Zhang, Yixian Huang, Song Li

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in AAPS PharmSciTech, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed.

  1. Review
  2. TetronicPharmaceutics · 2026
    Article
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yifei ZhangCenter for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania, 15261, USA.
Yixian Huang
Song Li

Funding

Targeted Combination Therapy for Breast CancerR01CA174305 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LI, SONG · 2014 to 2018
$1.6M
Rational Design of Lipidic Vectors for Mitochondria-Targeted AntioxidantsR01GM102989 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LI, SONG · 2013 to 2016
$1.1M
Nanomicellar Formulation for Synergistic Targeting of Prostate CancerR21CA173887 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LI, SONG · 2013 to 2014
$361k
NCI NIH HHS R01 CA174305NCI NIH HHS R01CA174305NCI NIH HHS R21 CA173887NCI NIH HHS R21CA173887NIGMS NIH HHS R01 GM102989NIGMS NIH HHS R01GM102989
6 · The paper itself

Abstract

Polymeric micelles represent an effective delivery system for poorly water-soluble anticancer drugs. With small size (10-100 nm) and hydrophilic shell of PEG, polymeric micelles exhibit prolonged circulation time in the blood and enhanced tumor accumulation. In this review, the importance of rational design was highlighted by summarizing the recent progress on the development of micellar formulations. Emphasis is placed on the new strategies to enhance the drug/carrier interaction for improved drug-loading capacity. In addition, the micelle-forming drug-polymer conjugates are also discussed which have both drug-loading function and antitumor activity.

Indexed as

Antineoplastic AgentsChemistry, PharmaceuticalDrug CarriersDrug Delivery SystemsHumansMicellesNeoplasmsPolymersAntineoplastic AgentsDrug CarriersMicellesPolymers

Identifiers

PMID24700296
PMCPMC4113619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.