Evidence map›Paper›PMID 24700194›Full record

ReviewThe American journal of psychiatry2014

Cognitive training in mental disorders: update and future directions.

Matcheri S Keshavan, Sophia Vinogradov, Judith Rumsey, Joel Sherrill, Ann Wagner

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The American journal of psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07309302 (Psychosocial Determinants and Impact of a Synchronous Remote Cognitive Remediation Program on Individuals With Post-Traumatic Stress Disorder.), which is not on this map. Cited by 127 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 16 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07309302 narecruitingnot on this mapstarted 2025, after this paper: background citation

Psychosocial Determinants and Impact of a Synchronous Remote Cognitive Remediation Program on Individuals With Post-Traumatic Stress Disorder.

TypeinterventionalSponsorUniversité du Québec a MontréalRan2025 to 2026Enrolled64ConditionsPost Traumatic Stress Disorder PTSDArmsCognitive Remediation Training, Control Group
3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 16 syntheses or guidelines pooled it.

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  9. Video Games for the Treatment of Autism Spectrum Disorder: A Systematic Review.Journal of autism and developmental disorders · 2022
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67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matcheri S Keshavan
Sophia Vinogradov
Judith Rumsey
Joel Sherrill
Ann Wagner

Funding

Cognitive Remediation of Schizophrenia in a Community Mental Health SettingR01MH068725 · NIMH · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI VINOGRADOV, SOPHIA · 2004 to 2014
$4.9M
Brain Imaging, Cognitive Enhancement and Early SchizophreniaR01MH092440 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KESHAVAN, MATCHERI S. · 2012 to 2016
$3.1M
Optimizing Cognitive Remediation Outcomes in SchizophreniaR01MH082818 · NIMH · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI VINOGRADOV, SOPHIA · 2009 to 2013
$2.9M
Rehabilitation, Brain Function and Early SchizophreniaR01MH060902 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KESHAVAN, MATCHERI S. · 2001 to 2005
$2.7M
Neuroscience-Guided Cognitive Remediation in Adolescents at Risk for PsychosisR01MH081051 · NIMH · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI VINOGRADOV, SOPHIA · 2008 to 2012
$2.4M
Cognitive Control in SchizophreniaR24MH081807 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CARTER, CAMERON S. · 2008 to 2010
$1.4M
NIMH NIH HHS MH060902NIMH NIH HHS MH068725NIMH NIH HHS MH081051NIMH NIH HHS MH081807NIMH NIH HHS MH082818NIMH NIH HHS MH092440NIMH NIH HHS R01 MH060902NIMH NIH HHS R01 MH068725NIMH NIH HHS R01 MH081051NIMH NIH HHS R01 MH082818NIMH NIH HHS R01 MH092440NIMH NIH HHS R24 MH081807
6 · The paper itself

Abstract

objectiveThis article reviews the conceptual basis, definitions, and evolution of cognitive training approaches for the treatment of mental disorders.

methodThe authors review the current state of the knowledge on cognitive training in psychiatric illnesses, and its neural and behavioral targets, and summarize the factors that appear to relate to a successful response, including learner characteristics that influence clinical outcome. They also discuss methodological issues relevant to the development and testing of cognitive training approaches, with the goal of creating maximally efficient and effective approaches to training. Finally, they identify gaps in existing knowledge and outline key research directions for the future.

resultsWhile much of the early research has been conducted in schizophrenia, cognitive training has more recently been applied to a widening range of neuropsychiatric illnesses, including attention deficit hyperactivity disorder, mood disorders, and substance use disorders. Cognitive training harnesses the inherent neuroplastic capacities of the brain, targeting neural system function across psychiatric disorders, thus improving the cognitive processes that play a role in emotion regulation, clinical symptoms, and adaptive community functioning.

conclusionsCognitive training offers considerable promise, especially given the limited efficacy of pharmacological interventions in ameliorating cognitive deficits. However, more research is needed to understand the mechanisms underlying cognitive training, predictors of response, generalization and real-world applicability, and approaches to dissemination in practice settings.

Indexed as

CognitionCognitive Behavioral TherapyHumansMental DisordersTreatment Outcome

Identifiers

PMID24700194
PMCPMC4114156

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.