Evidence map›Paper›PMID 24700073›Full record

ArticleJournal of medical virology2014

Phylogenetic analysis of rubella viruses identified in Uganda, 2003-2012.

Prossy Namuwulya, Emily Abernathy, Henry Bukenya, Josephine Bwogi, Phionah Tushabe, Molly Birungi, Ronald Seguya, Theopista Kabaliisa, Vincent P Alibu, Jonathan K Kayondo and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of medical virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

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  12. Epidemiological and molecular investigation of a rubella outbreak, Romania, 2011 to 2012.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2016
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  15. Genomic characterization of a persistent rubella virus from a case of Fuch' uveitis syndrome in a 73 year old man.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Prossy NamuwulyaUganda Virus Research Institute, Entebbe, Uganda.
Emily Abernathy
Henry Bukenya
Josephine Bwogi
Phionah Tushabe
Molly Birungi
Ronald Seguya
Theopista Kabaliisa
Vincent P Alibu
Jonathan K Kayondo
Pierre Rivailler
Joseph Icenogle
Barnabas Bakamutumaho
Uganda Virus Research Institute · UGCenters for Disease Control and Prevention · USMakerere University · UGNational Center for Immunization and Respiratory Diseases · US

Funding

Wellcome Trust 087540Wellcome Trust 100891
6 · The paper itself

Abstract

Molecular data on rubella viruses are limited in Uganda despite the importance of congenital rubella syndrome (CRS). Routine rubella vaccination, while not administered currently in Uganda, is expected to begin by 2015. The World Health Organization recommends that countries without rubella vaccination programs assess the burden of rubella and CRS before starting a routine vaccination program. Uganda is already involved in integrated case-based surveillance, including laboratory testing to confirm measles and rubella, but molecular epidemiologic aspects of rubella circulation have so far not been documented in Uganda. Twenty throat swab or oral fluid samples collected from 12 districts during routine rash and fever surveillance between 2003 and 2012 were identified as rubella virus RNA positive and PCR products encompassing the region used for genotyping were sequenced. Phylogenetic analysis of the 20 sequences identified 19 genotype 1G viruses and 1 genotype 1E virus. Genotype-specific trees showed that the Uganda viruses belonged to specific clusters for both genotypes 1G and 1E and grouped with similar sequences from neighboring countries. Genotype 1G was predominant in Uganda. More epidemiological and molecular epidemiological data are required to determine if genotype 1E is also endemic in Uganda. The information obtained in this study will assist the immunization program in monitoring changes in circulating genotypes.

Indexed as

Genetic VariationAdolescentAdultChildCluster AnalysisFemaleGenotypeHumansMaleMolecular EpidemiologyMolecular Sequence DataMouth MucosaPharynxPhylogenyPolymerase Chain ReactionRNA, ViralRNA, Viralgenotypemolecular characterizationrubella epidemiologysequences

Identifiers

PMID24700073
PMCPMC4269980
OpenAlexW2120715392

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.