Evidence map›Paper›PMID 24700055›Full record

ReviewReproductive sciences (Thousand Oaks, Calif.)2015

The endometriotic tissue lining the internal surface of endometrioma: hormonal, genetic, epigenetic status, and gene expression profile.

Ana Maria Sanchez, Paola Viganò, Edgardo Somigliana, Raffaella Cioffi, Paola Panina-Bordignon, Massimo Candiani

Open access · bronzeAbstract readReview
In one paragraph

Review in Reproductive sciences (Thousand Oaks, Calif.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Impact of Endometriosis on Pregnancy.Journal of personalized medicine · 2024
    Review
  8. Article
  9. Article
  10. DNA methylation in endometriosis (Review).Molecular medicine reports · 2016
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ana Maria SanchezDivision of Genetics and Cell Biology, Reproductive Sciences Laboratory, San Raffaele Scientific Institute, Milano, Italy.
Paola ViganòObstetrics and Gynecology Unit, San Raffaele Scientific Institute, Milano, Italy vigano.paola@hsr.it.
Edgardo SomiglianaDepartment of Obstetrics, Gynecology and Neonatology, Fondazione Cà Granda, Ospedale Maggiore Policlinico, Milano, Italy.
Raffaella CioffiObstetrics and Gynecology Unit, San Raffaele Scientific Institute, Milano, Italy.
Paola Panina-BordignonDivision of Genetics and Cell Biology, Reproductive Sciences Laboratory, San Raffaele Scientific Institute, Milano, Italy.
Massimo CandianiObstetrics and Gynecology Unit, San Raffaele Scientific Institute, Milano, Italy Obstetrics and Gynecology Unit, San Raffaele Scientific Institute, Vita-Salute University, Milano, Italy.
San Raffaele University of Rome · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian endometriomas are found in a consistent proportion of patients with endometriosis and are associated with a more severe form of the disease. The endometriotic tissue lining the inside of the endometrioma has been extensively studied over the years mostly for the need to compare the molecular and cellular characteristics of eutopic and ectopic endometria. Several aspects of hormonal regulation, response to local inflammation, carcinogenesis, and modifications of the local environment have been investigated in order to characterize also the processes associated with peritoneal endometriosis. In this review, we have summarized the current knowledge of pathophysiology of endometrioma, with a particular focus on the cellular components lining the internal surface of the cyst in order to provide a comprehensive overview of the hormonal, genetic, epigenetic, and gene expression profiles of this essential part of the cyst.

Indexed as

Epigenesis, GeneticGene Expression ProfilingAnimalsEmbryo ImplantationEndometriosisEndometriumFemaleGene Expression RegulationGenetic MarkersGenetic Predisposition to DiseaseHormonesHumansInfertility, FemalePhenotypeRisk FactorsGenetic MarkersHormonesendometriomagene expressionoxidative status

Identifiers

PMID24700055
PMCPMC4812685
OpenAlexW2020756384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.