Evidence map›Paper›PMID 24699632›Full record

ArticleJournal of biomedical optics2014

Four-dimensional motility tracking of biological cells by digital holographic microscopy.

Xiao Yu, Jisoo Hong, Changgeng Liu, Michael Cross, Donald T Haynie, Myung K Kim

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Quantitative assessment of cancer cell morphology and motility using telecentric digital holographic microscopy and machine learning.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2018
    Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiao YuUniversity of South Florida, Department of Physics, Digital Holography and Microscopy Laboratory, Tampa, Florida 33620.
Jisoo HongUniversity of South Florida, Department of Physics, Digital Holography and Microscopy Laboratory, Tampa, Florida 33620.
Changgeng LiuUniversity of South Florida, Department of Physics, Digital Holography and Microscopy Laboratory, Tampa, Florida 33620.
Michael CrossUniversity of South Florida, Department of Physics, Nanomedicine and Nanobiotechnology Laboratory, Tampa, Florida 33620.
Donald T HaynieUniversity of South Florida, Department of Physics, Nanomedicine and Nanobiotechnology Laboratory, Tampa, Florida 33620.
Myung K KimUniversity of South Florida, Department of Physics, Digital Holography and Microscopy Laboratory, Tampa, Florida 33620.

Funding

Digital holographic adaptive optics for retinal imaging without wavefront sensorR21EY021876 · NEI · UNIVERSITY OF SOUTH FLORIDA · PI KIM, MYUNG K · 2012 to 2013
$394k
NEI NIH HHS R21EY021876
6 · The paper itself

Abstract

Three-dimensional profiling and tracking by digital holography microscopy (DHM) provide label-free and quantitative analysis of the characteristics and dynamic processes of objects, since DHM can record real-time data for microscale objects and produce a single hologram containing all the information about their three-dimensional structures. Here, we have utilized DHM to visualize suspended microspheres and microfibers in three dimensions, and record the four-dimensional trajectories of free-swimming cells in the absence of mechanical focus adjustment. The displacement of microfibers due to interactions with cells in three spatial dimensions has been measured as a function of time at subsecond and micrometer levels in a direct and straightforward manner. It has thus been shown that DHM is a highly efficient and versatile means for quantitative tracking and analysis of cell motility.

Indexed as

Cell MovementCell TrackingCryptophytaHolographyModels, Biological

Identifiers

PMID24699632
PMCPMC3974550

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.