Evidence map›Paper›PMID 24698454›Full record

Observational studyThe Journal of pediatrics2014

The effect of abnormal birth history on ambulatory blood pressure and disease progression in children with chronic kidney disease.

Joseph T Flynn, Derek K Ng, Grace J Chan, Joshua Samuels, Susan Furth, Bradley Warady, Larry A Greenbaum, Chronic Kidney Disease in Children Study

Registry-linked trialOpen access · greenAbstract readObservational Study
In one paragraph

Observational study in The Journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00327860 (Chronic Kidney Disease in Children Prospective Cohort Study), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
22.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00327860 recruitingnot on this map

Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)

TypeobservationalSponsorJohns Hopkins Bloomberg School of Public HealthRan2003 to 2028Enrolled1,300ConditionsChronic Kidney Disease
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. APOL1-associated glomerular disease among African-American children: a collaboration of the Chronic Kidney Disease in Children (CKiD) and Nephrotic Syndrome Study Network (NEPTUNE) cohorts.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2017
    Article
  5. Review
  6. Averting the legacy of kidney disease - focus on childhood.African journal of primary health care & family medicine · 2016
    Review
  7. Averting the Legacy of Kidney Disease--Focus on Childhood.American journal of hypertension · 2016
    Article
  8. Averting the Legacy of Kidney Disease - Focus on Childhood.Kidney diseases (Basel, Switzerland) · 2016
    Article
  9. Article
  10. Review
  11. Article
  12. Averting the legacy of kidney disease - focus on childhood.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2016
    Review
  13. Averting the Legacy of Kidney Disease: Focus on Childhood.International journal of organ transplantation medicine · 2016
    Article
  14. Article
  15. [In time: averting the legacy of kidney disease - focus on childhood].Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Joseph T FlynnDivision of Nephrology, Seattle Children's Hospital, and Department of Pediatrics, University of Washington School of Medicine, Seattle, WA. Electronic address: joseph.flynn@seattlechildrens.org.
Derek K NgDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Grace J ChanDivision of Medicine Critical Care, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.
Joshua SamuelsDivision of Pediatric Nephrology and Hypertension, Department of Pediatrics, University of Texas Medical School at Houston, Houston, TX.
Susan FurthDivision of Nephrology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA.
Bradley WaradyDivision of Nephrology, Children's Mercy Hospital, and Department of Pediatrics, University of Missouri-Kansas City, Kansas City, MO.
Larry A GreenbaumDivision of Pediatric Nephrology, Children's Healthcare of Atlanta, and Department of Pediatrics, Emory University, Atlanta, GA.
Chronic Kidney Disease in Children Study
Children's Mercy Hospital · USEmory University · USHarvard University · USJohns Hopkins University · USPhiladelphia University · USUniversity of Washington · US

Funding

Chronic Kidney Disease in Children Study (C-Kid)U01DK066174 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SUSAN L. FURTH · 2003 to 2026
$25.1M
CKiD Cardiovascular Testing Travel SupplementU01DK066143 · NIDDK · CHILDREN'S MERCY HOSP (KANSAS CITY, MO) · PI Bradley Alan Warady · 2003 to 2026
$24.2M
The Kidney Disease in Children Data Management and Analysis Center (KIDMAC)U01DK066116 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MUNOZ, ALVARO · 2003 to 2017
$17.9M
Central Biochemistry Laboratory of the CKiD ConsortiumU01DK082194 · NIDDK · UNIVERSITY OF ROCHESTER · PI SCHWARTZ, GEORGE J · 2008 to 2017
$3.5M
NIDDK NIH HHS U01 DK066116NIDDK NIH HHS U01 DK066143NIDDK NIH HHS U01 DK066174NIDDK NIH HHS U01 DK082194NIDDK NIH HHS U01DK-082194NIDDK NIH HHS U01-DK-66116NIDDK NIH HHS U01-DK-66143NIDDK NIH HHS U01-DK-66174
6 · The paper itself

Abstract

objectiveTo examine the associations between abnormal birth history (birth weight <2500 g, gestational age <36 weeks, or small for gestational age), blood pressure (BP), and renal function among 332 participants (97 with abnormal and 235 with normal birth history) in the Chronic Kidney Disease in Children Study, a cohort of children with chronic kidney disease (CKD). STUDY

designCasual and 24-hour ambulatory BP were obtained. Glomerular filtration rate (GFR) was determined by iohexol disappearance. Confounders (birth and maternal characteristics, socioeconomic status) were used to generate predicted probabilities of abnormal birth history for propensity score matching. Weighted linear and logistic regression models with adjustment for quintiles of propensity scores and CKD diagnosis were used to assess the impact of birth history on BP and GFR.

resultsAge at enrollment, percent with glomerular disease, and baseline GFR were similar between the groups. Those with abnormal birth history were more likely to be female, of Black race or Hispanic ethnicity, to have low household income, or part of a multiple birth. Unadjusted BP measurements, baseline GFR, and change in GFR did not differ significantly between the groups; no differences were seen after adjusting for confounders by propensity score matching.

conclusionsAbnormal birth history does not appear to have exerted a significant influence on BP or GFR in this cohort of children with CKD. The absence of an observed association is likely secondary to the dominant effects of underlying CKD and its treatment.

Indexed as

Reproductive HistoryAdolescentBlood PressureBlood Pressure Monitoring, AmbulatoryChildCohort StudiesDisease ProgressionFemaleGlomerular Filtration RateHeart RateHumansMalePropensity ScoreProspective StudiesRegression AnalysisRenal Insufficiency, Chronic

Identifiers

PMID24698454
PMCPMC4074552
OpenAlexW2061816743

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.