Evidence map›Paper›PMID 24697316›Full record

ReviewAllergy2014

Environmental exposures and asthma morbidity in children living in urban neighborhoods.

E C Matsui

Abstract readReview
In one paragraph

Review in Allergy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Factors associated with high short-acting β2-agonist use in urban children with asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2015
    Trial
  4. Stress and Quality of Life in Urban Caregivers of Children With Poorly Controlled Asthma: A Longitudinal Analysis.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners
    Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The influence of urban exposures and residence on childhood asthma.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Review
  13. Article
  14. Asthma and the social determinants of health.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
  15. Housing and asthma disparities.The Journal of allergy and clinical immunology · 2021
    Article
  16. Review
  17. Article
  18. Obesity may enhance the adverse effects of NOThe Journal of allergy and clinical immunology · 2020
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

E C MatsuiDivision of Pediatric Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Johns Hopkins Medicine · US

Funding

Oxidative Stress & Inflammation in a Human PM Nasal ChallengeP50ES015903 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI BREYSSE, PATRICK N · 2007 to 2011
$12.1M
Mouse Allergen and Asthma Intervention TrialU01AI083238 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2010 to 2014
$7.9M
Project 3: Dissecting the Diet Asthma Relationship in Mice Models of AsthmaP01ES018176 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI DIETTE, GREGORY B · 2009 to 2013
$4.2M
Mouse Allergen and Inner-City AsthmaR01AI070630 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2006 to 2010
$1.9M
NIAID NIH HHS R01 AI070630NIAID NIH HHS R01AI070630NIAID NIH HHS U01 AI083238NIAID NIH HHS U01AI083238NIEHS NIH HHS P01 ES018176NIEHS NIH HHS P01ES018176NIEHS NIH HHS P50 ES015903NIEHS NIH HHS P50ES015903
6 · The paper itself

Abstract

A substantial disparity in asthma prevalence and morbidity among urban children compared with their nonurban counterparts has been recognized for more than two decades. Because of the nature of urban neighborhoods, pest allergens, such as cockroach and mouse, are present in high concentrations in US urban housing and have both repeatedly been linked to asthma morbidity in sensitized children. In addition, there is a growing body of evidence demonstrating that concentrations of many pollutants are higher indoors than outdoors in both US and European urban communities and that exposures to indoor pollutants such as particulate matter (PM) and nitrogen dioxide (NO2 ) are independently associated with symptoms in children with asthma. Although environmental interventions are challenging to implement, when they reduce relevant indoor allergen and pollutant exposures, they are associated with clear improvements in asthma. Other modifiable risk factors in urban childhood asthma that have emerged include dietary and nutritional factors. Overweight and obese children, for example, may be more susceptible to the pulmonary effects of pollutant exposure. Insufficiency of vitamin D and folate has also emerged as modifiable risk factors for asthma morbidity in children. The identification of these modifiable risk factors for urban childhood asthma morbidity offers a ripe opportunity for intervention.

Indexed as

Urban PopulationAir Pollution, IndoorAllergensAnimalsAsthmaChildEnvironmental ExposureHumansPrevalenceRisk FactorsAllergenschildhood asthmafolateindoor allergensindoor pollutantsmouse allergen

Identifiers

PMID24697316
PMCPMC3983559
OpenAlexW1970397466

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.